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Results for “Transfusion-Dependent Thalassemia”

131 trials

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Showing 20 of 131 results

Not applicableActive Not RecruitingNCT05860595
What this trial is testing

Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Early research (Phase 1)Looking for participantsNCT06647979
What this trial is testing

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Beta-Thalassemia+1 more
Daniel Bauer 10
Not applicableActive Not RecruitingNCT06875219
What this trial is testing

To Evaluate Long- Term Safety and Efficacy of Luspatercept

Who this might be right for
Thalassemia Major
Fondazione per la Ricerca sulle Anemie ed Emoglobinopatie in Italia 350
Testing effectiveness (Phase 2)Study completedNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 100
Very early researchLooking for participantsNCT05864170
What this trial is testing

The Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
β-thalassemia
Shenzhen Hemogen 3
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Early research (Phase 1)Study completedNCT06098014
What this trial is testing

Safety & Efficacy of Thalidomide in Children With Transfusion Dependent Thalassemia

Who this might be right for
Transfusion-dependent Thalassemia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 60
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Large-scale testing (Phase 3)Active Not RecruitingNCT05356195
What this trial is testing

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Who this might be right for
Beta-ThalassemiaThalassemiaGenetic Diseases, Inborn+2 more
Vertex Pharmaceuticals Incorporated 16
Testing effectiveness (Phase 2)WithdrawnNCT04938635
What this trial is testing

Efficacy and Safety Study of Multiple Doses of VIT-2763 in Adults With Transfusion-dependent Beta-thalassemia

Who this might be right for
Beta-Thalassemia
Vifor (International) Inc.
Testing effectiveness (Phase 2)Study completedNCT00901199
What this trial is testing

Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload

Who this might be right for
ThalassemiaIron Overload
Elliott Vichinsky 22
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
Testing effectiveness (Phase 2)Study completedNCT01740713
What this trial is testing

Pharmacokinetic Study of Deferiprone in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 23
Post-approval studies (Phase 4)Study completedNCT06606886
What this trial is testing

Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

Who this might be right for
Transfusion Dependent Beta-thalassemia
Bahria University 96
Early research (Phase 1)Looking for participantsNCT06465550
What this trial is testing

Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 9
Testing effectiveness (Phase 2)Ended earlyNCT03381833
What this trial is testing

A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia

Who this might be right for
Beta-Thalassemia
La Jolla Pharmaceutical Company 84
Testing effectiveness (Phase 2)WithdrawnNCT03801889
What this trial is testing

SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias

Who this might be right for
Iron OverloadBeta-Thalassemia
Abfero Pharmaceuticals, Inc
Not applicableLooking for participantsNCT07215975
What this trial is testing

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Who this might be right for
β-thalassemia
Bristol-Myers Squibb 200
Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
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