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Results for “Transfusion-dependent β-thalassemia Patients”

20 trials

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Showing 20 of 20 results

Very early researchLooking for participantsNCT05864170
What this trial is testing

The Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
β-thalassemia
Shenzhen Hemogen 3
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
Early research (Phase 1)Looking for participantsNCT06465550
What this trial is testing

Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07721480
What this trial is testing

Gene Therapy for Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
Beta Thalassemia Transfusion Dependent
Prince of Wales Hospital, Shatin, Hong Kong 6
Not applicableLooking for participantsNCT07207577
What this trial is testing

Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD

Who this might be right for
Beta Thalassemia Transfusion Dependent
Centre Hospitalier Metropole Savoie 36
Not applicableUnknownNCT06041620
What this trial is testing

Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells

Who this might be right for
Thalassemia, BetaThalassemia Major
Institute of Hematology & Blood Diseases Hospital, China 2
Early research (Phase 1)Looking for participantsNCT06772766
What this trial is testing

A Multiple Ascending Dose Study of 9MW3011 in Patients With Non-transfusion-dependent β-thalassemia

Who this might be right for
Beta-Thalassemia
Mabwell (Shanghai) Bioscience Co., Ltd. 40
Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Very early researchNot Yet RecruitingNCT07190001
What this trial is testing

YOLT-204 in Patients With Hemoglobinopathies

Who this might be right for
Hemoglobinopathies (Transfusion-dependent β-thalassemia and Sickle Cell Disease)
Guangzhou Women and Children's Medical Center 18
Early research (Phase 1)Study completedNCT02950857
What this trial is testing

EPEG in Beta Thalassemia Patients

Who this might be right for
Beta-Thalassemia
Prolong Pharmaceuticals 6
Not applicableLooking for participantsNCT06219239
What this trial is testing

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Early research (Phase 1)Looking for participantsNCT06655662
What this trial is testing

Evaluating Safety and Efficacy of Lentiviral-transduced CD34+ HSCs in Β-thalassaemia Patients.

Who this might be right for
Β-thalassemia
Shenzhen Hemogen 8
Not applicableUnknownNCT06164821
What this trial is testing

Clinical Observation of Luspatercept in Treatment of Chinese Adult β-thalassaemia Patients With TD β-thalassemia

Who this might be right for
Effect of Drug
Hematology department of the 920th hospital 10
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Testing effectiveness (Phase 2)Looking for participantsNCT07338344
What this trial is testing

Evaluating the Clinical Efficacy and Safety of Luspatercept Combined With Thalidomide in the Treatment of β-TDT Patients

Who this might be right for
Transfusion-dependent β-thalassemia Patients
Rongrong Liu 78
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Looking for participantsNCT06302491
What this trial is testing

Safety and Efficiency of AND017 in Patients With β-thalassemia

Who this might be right for
β -Thalassemia
Kind Pharmaceuticals LLC 64
Not applicableLooking for participantsNCT05776173
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent β-thalassemia

Who this might be right for
β-thalassemia Major
Shanghai BDgene Co., Ltd. 10
Testing effectiveness (Phase 2)Ended earlyNCT04059406
What this trial is testing

Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)

Who this might be right for
Beta Thalassemia Intermedia
Ionis Pharmaceuticals, Inc. 29
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