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Results for “Transfusion-dependent Thalassemia”

131 trials

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Showing 20 of 131 results

Post-approval studies (Phase 4)Study completedNCT06606886
What this trial is testing

Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

Who this might be right for
Transfusion Dependent Beta-thalassemia
Bahria University 96
Not applicableEnded earlyNCT00578292
What this trial is testing

Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO

Who this might be right for
Thalassemia
Baylor College of Medicine 10
Testing effectiveness (Phase 2)WithdrawnNCT01948817
What this trial is testing

Deferasirox BID (Twice a Day) in Transfusion Dependent Thalassemia Patients With Inadequate Response to High Doses

Who this might be right for
Focus on Transfusion Dependent Thalassemia Patients Who Are Inadequate Responders to Deferasirox > 35mg/kgQD
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Not applicableLooking for participantsNCT05991336
What this trial is testing

Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy

Who this might be right for
Transfusion-dependent Beta-ThalassemiaGene Therapy
Institute of Hematology & Blood Diseases Hospital, China 100
Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
Not applicableNot Yet RecruitingNCT07660224
What this trial is testing

The Effect of Motivational Interviewing on Treatment Adherence and Self-Efficacy Among Omani Adults With Thalassemia

Who this might be right for
Beta-Thalassemia MajorTransfusion-Dependent Thalassemia
Oman Ministry of Health 45
Testing effectiveness (Phase 2)Looking for participantsNCT07680803
What this trial is testing

Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Fondazione Telethon 9
Post-approval studies (Phase 4)Study completedNCT06299670
What this trial is testing

Efficacy of Combination of Hdroxyurea and Thalidomide Over Hydroxyurea or Thalidomide in the Treatment of Transfusion Dependent Thalassemia in Children

Who this might be right for
Transfusion-dependent Thalassemia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 90
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Large-scale testing (Phase 3)Study completedNCT03651102
What this trial is testing

Efficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia

Who this might be right for
Thalassemia
Blood Diseases Clinic 654
Not applicableEnded earlyNCT05752123
What this trial is testing

Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects with Transfusion Dependent Β-Thalassaemia.

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 2
Not applicableActive Not RecruitingNCT05860595
What this trial is testing

Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Not applicableLooking for participantsNCT07215975
What this trial is testing

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Who this might be right for
β-thalassemia
Bristol-Myers Squibb 200
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Large-scale testing (Phase 3)Study completedNCT03655678
What this trial is testing

A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia

Who this might be right for
Beta-ThalassemiaThalassemiaGenetic Diseases, Inborn+2 more
Vertex Pharmaceuticals Incorporated 59
Testing effectiveness (Phase 2)Study completedNCT00879242
What this trial is testing

Effect of Deferasirox on Patients With Cardiac MRI T2* < 20 Msec

Who this might be right for
Beta Thalassemia Transfusion Dependent
Novartis Pharmaceuticals 20
Large-scale testing (Phase 3)Looking for participantsNCT07506863
What this trial is testing

Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 54
Post-approval studies (Phase 4)Study completedNCT03591575
What this trial is testing

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children

Who this might be right for
Beta Thalassemia Major AnemiaIron Overload
Chiesi Canada Corp 64
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
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