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Results for “Transfusion-dependent Thalassemia”

125 trials

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Showing 20 of 125 results

Not applicableStudy completedNCT06509581
What this trial is testing

Vitamin E Supplementation for Children With Transfusion Dependent Beta Thalassemia on Different Iron Chelation Regimen

Who this might be right for
Beta-Thalassemia
Ain Shams University 180
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Not applicableEnded earlyNCT00578292
What this trial is testing

Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO

Who this might be right for
Thalassemia
Baylor College of Medicine 10
Not applicableStudy completedNCT01874405
What this trial is testing

Retrospective Evaluation of Adult and Pediatric Transfusion-dependent Patients Treated With Deferasirox Therapy

Who this might be right for
Iron Overload
University of Campania Luigi Vanvitelli 80
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Post-approval studies (Phase 4)Study completedNCT00749515
What this trial is testing

Pilot Study for Patients With Poor Response to Deferasirox

Who this might be right for
Transfusion-dependent HemachromatosisThalassemia MajorSickle Cell Disease
Boston Children's Hospital 15
Large-scale testing (Phase 3)Study completedNCT00171821
What this trial is testing

A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload

Who this might be right for
Transfusion-dependent Iron Overload
Novartis Pharmaceuticals 1,784
Large-scale testing (Phase 3)Study completedNCT03651102
What this trial is testing

Efficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia

Who this might be right for
Thalassemia
Blood Diseases Clinic 654
Post-approval studies (Phase 4)Study completedNCT03032666
What this trial is testing

Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial

Who this might be right for
ThalassemiaHepatitis C
Ala'a Sharara 7
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623
What this trial is testing

The BENeFiTS Trial in Beta Thalassemia Intermedia

Who this might be right for
Beta Thalassemia IntermediaSickle Cell Disease
Phoenicia BioScience 36
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableStudy completedNCT02198508
What this trial is testing

Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia Patients

Who this might be right for
Beta-thalassemia Major
China Medical University Hospital 13
Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Testing effectiveness (Phase 2)Study completedNCT03271541
What this trial is testing

Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-Thalassemia

Who this might be right for
Beta-Thalassemia
Hoffmann-La Roche 12
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Testing effectiveness (Phase 2)Looking for participantsNCT05664737
What this trial is testing

Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

Who this might be right for
Anemia
Bristol-Myers Squibb 189
Not applicableLooking for participantsNCT07207577
What this trial is testing

Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD

Who this might be right for
Beta Thalassemia Transfusion Dependent
Centre Hospitalier Metropole Savoie 36
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Not applicableActive Not RecruitingNCT03275051
What this trial is testing

Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)

Who this might be right for
Beta Thalassaemia
IRCCS San Raffaele 9
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