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Results for “Transfusion-dependent Thalassemia”

122 trials

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Showing 20 of 122 results

Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Testing effectiveness (Phase 2)Study completedNCT00349453
What this trial is testing

Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Who this might be right for
Hemochromatosis
Lipomed 24
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableLooking for participantsNCT06219239
What this trial is testing

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Large-scale testing (Phase 3)Looking for participantsNCT05356195
What this trial is testing

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Who this might be right for
Beta-ThalassemiaThalassemiaGenetic Diseases, Inborn+2 more
Vertex Pharmaceuticals Incorporated 15
Not applicableUnknownNCT02067130
What this trial is testing

Utility of Fibroscan in Estimating Hepatic Iron Concentration

Who this might be right for
Hereditary Anemias
University of British Columbia 30
Testing effectiveness (Phase 2)Study completedNCT07370922
What this trial is testing

Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Ain Shams University 80
Post-approval studies (Phase 4)WithdrawnNCT02069886
What this trial is testing

Effect of Deferasirox on Endocrine Complications in Subjects With Transfusion Dependent Thalassemia

Who this might be right for
Thalassemia (Transfusion Delendent)
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 150
Post-approval studies (Phase 4)Study completedNCT03992001
What this trial is testing

Impact of the Preparation Method of Red Cell Concentrates on Transfusion Indices in Thalassemic Patients

Who this might be right for
Thalassemia Major
Università degli Studi di Ferrara 55
Not applicableNot Yet RecruitingNCT07215975
What this trial is testing

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Who this might be right for
β-thalassemia
Bristol-Myers Squibb 200
Not applicableLooking for participantsNCT05991336
What this trial is testing

Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy

Who this might be right for
Transfusion-dependent Beta-ThalassemiaGene Therapy
Institute of Hematology & Blood Diseases Hospital, China 100
Testing effectiveness (Phase 2)Ended earlyNCT04059406
What this trial is testing

Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)

Who this might be right for
Beta Thalassemia Intermedia
Ionis Pharmaceuticals, Inc. 29
Post-approval studies (Phase 4)Study completedNCT00749515
What this trial is testing

Pilot Study for Patients With Poor Response to Deferasirox

Who this might be right for
Transfusion-dependent HemachromatosisThalassemia MajorSickle Cell Disease
Boston Children's Hospital 15
Testing effectiveness (Phase 2)Looking for participantsNCT06657391
What this trial is testing

Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent Thalassemia

Who this might be right for
Transfusion Dependent Thalassemia
Rongrong Liu 396
Testing effectiveness (Phase 2)Study completedNCT02993224
What this trial is testing

Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet

Who this might be right for
Transfusion-dependent ThalassemiaNon-transfusion-dependent Thalassemia
Novartis Pharmaceuticals 148
Large-scale testing (Phase 3)Study completedNCT02604433
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia

Who this might be right for
Erythrocyte TransfusionBeta-Thalassemia
Celgene 336
Post-approval studies (Phase 4)Active Not RecruitingNCT05891249
What this trial is testing

Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Who this might be right for
Anemia
Bristol-Myers Squibb 85
Testing effectiveness (Phase 2)Study completedNCT03432364
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Who this might be right for
Transfusion Dependent Beta-thalassemia
Sangamo Therapeutics 5
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
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