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Results for “Transfusion-dependent Thalassemia”

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Showing 20 of 0 results

Post-approval studies (Phase 4)Study completedNCT03032666
What this trial is testing

Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial

Who this might be right for
ThalassemiaHepatitis C
Ala'a Sharara 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 19
Testing effectiveness (Phase 2)Study completedNCT00901199
What this trial is testing

Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload

Who this might be right for
ThalassemiaIron Overload
Elliott Vichinsky 22
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Not applicableNot Yet RecruitingNCT07774351
What this trial is testing

A Clinical Exploratory Study of YOLT-204 in the Treatment of Hemoglobinopathies

Who this might be right for
Hemoglobinopathies
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 30
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623
What this trial is testing

The BENeFiTS Trial in Beta Thalassemia Intermedia

Who this might be right for
Beta Thalassemia IntermediaSickle Cell Disease
Phoenicia BioScience 36
Testing effectiveness (Phase 2)Looking for participantsNCT06490627
What this trial is testing

Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia

Who this might be right for
Fetal HemoglobinThalassemia MajorGenetic Disease
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 54
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Early research (Phase 1)Looking for participantsNCT06655662
What this trial is testing

Evaluating Safety and Efficacy of Lentiviral-transduced CD34+ HSCs in Β-thalassaemia Patients.

Who this might be right for
Β-thalassemia
Shenzhen Hemogen 8
Not applicableNot Yet RecruitingNCT07796022
What this trial is testing

Clinical, Economic,and Psychosocial Burden of Thalassemia in Sohag

Who this might be right for
Thalassemia Particularly Transfusion Dependent Thalassemia
Randa Elham Hamam 100
Testing effectiveness (Phase 2)Looking for participantsNCT06657391
What this trial is testing

Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent Thalassemia

Who this might be right for
Transfusion Dependent Thalassemia
Rongrong Liu 396
Post-approval studies (Phase 4)Study completedNCT01709838
What this trial is testing

Efficacy and Safety Study of Deferasirox in Patients With Non-transfusion Dependent Thalassemia

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 134
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Post-approval studies (Phase 4)Study completedNCT00564941
What this trial is testing

Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload

Who this might be right for
Myelodysplastic SyndromesBeta-Thalassemia
Novartis Pharmaceuticals 309
Testing effectiveness (Phase 2)Study completedNCT03432364
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Who this might be right for
Transfusion Dependent Beta-thalassemia
Sangamo Therapeutics 5
Large-scale testing (Phase 3)Study completedNCT07210450
What this trial is testing

Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia

Who this might be right for
Pulmonary Artery PressureThalassemiaNon-transfusion Dependent Thalassemia
Mazandaran University of Medical Sciences 8
Early research (Phase 1)Looking for participantsNCT06465550
What this trial is testing

Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 9
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
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