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Results for “Transthyretin”

235 trials

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Showing 20 of 235 results

Post-approval studies (Phase 4)Study completedNCT04828993
What this trial is testing

The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients

Who this might be right for
Transthyretin Amyloid Polyneuropathy (ATTR-PN)
Pfizer 15
Large-scale testing (Phase 3)Looking for participantsNCT07207811
What this trial is testing

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S 1,280
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT03536767
What this trial is testing

Open-Label Study of AG10 in Patients with Cardiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
Eidos Therapeutics, a BridgeBio company 55
Not applicableEnded earlyNCT05259072
What this trial is testing

CarDIo-ttranSSfOrm nucLEar Imaging Study

Who this might be right for
AmyloidosisTransthyretin Amyloid Cardiomyopathy
Oregon Health and Science University 4
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableUnknownNCT05896904
What this trial is testing

Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure
Aarhus University Hospital Skejby 100
Not applicableLooking for participantsNCT07213297
What this trial is testing

Comprehensive Program for Hereditary Transthyretin Amyloidosis

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, Familial
Hospital de Alta Complejidad en Red 20
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Not applicableLooking for participantsNCT07205666
What this trial is testing

The Eplontersen Pregnancy and Lactation Outcomes Study

Who this might be right for
Transthyretin Amyloidosis
AstraZeneca 10
Not applicableWithdrawnNCT02713880
What this trial is testing

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Who this might be right for
Transthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin Amyloid Cardiopathy
CENTOGENE GmbH Rostock
Not applicableStudy completedNCT04201418
What this trial is testing

Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Who this might be right for
Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy
Alnylam Pharmaceuticals 67
Testing effectiveness (Phase 2)Looking for participantsNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Not applicableStudy completedNCT01432587
What this trial is testing

The Effect of Diflunisal on Familial Transthyretin Amyloidosis

Who this might be right for
Amyloidosis
Umeå University 55
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Not applicableStudy completedNCT03322319
What this trial is testing

Frequency of Cardiac Amyloidosis in the Caribbean's. (TEAM Amylose)

Who this might be right for
Left Ventricular Hypertrophy
University Hospital Center of Martinique 175
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