Not applicableApproved For MarketingNCT03400098What this trial is testingATTR Expanded Access Program (EAP) by IonisWho this might be right forAmyloidosis, Hereditary Ionis Pharmaceuticals, Inc.
Not applicableStudy completedNCT05560555What this trial is testingRetrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.Who this might be right forHereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy Pfizer 5
Not applicableLooking for participantsNCT04535349What this trial is testingQuantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR AmyloidosisWho this might be right forAmyloidosis Transthyretin University Hospital, Caen 35
Not applicableLooking for participantsNCT07196839What this trial is testingDetermining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker StudyWho this might be right forTransthyretin (TTR) Amyloid Cardiomyopathy University of Texas Southwestern Medical Center 50
Not applicableStudy completedNCT03190577What this trial is testingAssessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown AetiologyWho this might be right forFamilial Amyloid NeuropathyTransthyretin Amyloidosis Nantes University Hospital 400
Not applicableUnknownNCT05087953What this trial is testingAutonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart DiseaseWho this might be right forAutonomic Nervous System DiseaseAmyloid Neuropathies University of Sao Paulo General Hospital 60
Not applicableNot Yet RecruitingNCT07343999What this trial is testingEFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac AmyloidosisWho this might be right forTransthyretin Cardiac Amyloidosis Universidad de Burgos 102
Not applicableEnded earlyNCT03328338What this trial is testingMitochondrial Function in Transthyretin AmyloidosisWho this might be right forCardiac Amyloidosis University Hospital Center of Martinique 12
Not applicableEnrolling By InvitationNCT07238426What this trial is testingATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, TurkeyWho this might be right forCardiac AmyloidosisTransthyretin Amyloidosis Kotyora Family Medicine Health Management and Education Association 800
Large-scale testing (Phase 3)WithdrawnNCT04418024What this trial is testingEfficacy and Safety of AG10 in Subjects with Transthyretin Amyloid PolyneurophathyWho this might be right forTransthyretin-Related (ATTR) Familial Amyloid Polyneuropathy Eidos Therapeutics, a BridgeBio company
Not applicableLooking for participantsNCT06034405What this trial is testingAnalysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac AmyloidosisWho this might be right forLumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more Columbia University 1,663
Not applicableStudy completedNCT03237494What this trial is testingTRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive SubjectsWho this might be right forTransthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy+2 more CENTOGENE GmbH Rostock 5,028
Not applicableLooking for participantsNCT06101108What this trial is testingEarly Diagnosis of Age-Linked CArdiac TransThyRetin Amyloidosis by Selective Screening in Spinal Stenosis SurgeryWho this might be right forTransthyretin Amyloid Cardiomyopathy Philippe Debonnaire 400
Early research (Phase 1)Study completedNCT02797847What this trial is testingA Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy SubjectsWho this might be right forTransthyretin-mediated Amyloidosis (ATTR Amyloidosis) Alnylam Pharmaceuticals 80
Not applicableLooking for participantsNCT06845644What this trial is testingLongitudinal Quantitative Neuromuscular MRI in Neuropathic PatientsWho this might be right forCharcot-Marie-Tooth Neuropathy Type 1AHereditary Transthyretin Amyloid NeuropathyAcquired Demyelinating Neuropathy Assistance Publique Hopitaux De Marseille 120
Large-scale testing (Phase 3)WithdrawnNCT04882735What this trial is testingEfficacy and Safety of Acoramidis (AG10) in Subjects with Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)Who this might be right forTransthyretin-Related (ATTR) Familial Amyloid Polyneuropathy Eidos Therapeutics, a BridgeBio company
Large-scale testing (Phase 3)Study completedNCT01994889What this trial is testingSafety and Efficacy of Tafamidis in Patients With Transthyretin CardiomyopathyWho this might be right forTransthyretin (TTR) Amyloid Cardiomyopathy Pfizer 441
Not applicableUnknownNCT05938218What this trial is testingVirtual Reality Assisted Patient Empowerment: Diagnose ATTR-Amyloidosis And Start TreatmentWho this might be right forAmyloidosis CardiacVirtual Reality Heinrich-Heine University, Duesseldorf 60
Not applicableActive Not RecruitingNCT07080268What this trial is testingValidation of a Questionnaire for Quality of Life Assessment in Patients With Transthyretin Amyloidosis.Who this might be right forAmyloidosis in Transthyretin (TTR)Hereditary Amyloidosis, Transthyretin-Related Hospital General de Niños Pedro de Elizalde 70
Testing effectiveness (Phase 2)Looking for participantsNCT06539208What this trial is testingA Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)Who this might be right forTransthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy YolTech Therapeutics Co., Ltd 31