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Results for “Transthyretin Amyloidosis (ATTR) With Cardiomyopathy”

76 trials

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Showing 20 of 76 results

Large-scale testing (Phase 3)Study completedNCT00935012
What this trial is testing

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Who this might be right for
ATTR-CMTTR-CM
Pfizer 31
Testing effectiveness (Phase 2)Study completedNCT05442047
What this trial is testing

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S 105
Not applicableStudy completedNCT06086353
What this trial is testing

Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Pfizer 6
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Large-scale testing (Phase 3)Not Yet RecruitingNCT06712030
What this trial is testing

Effect of Angiotensin Receptor/Neprilysin Inhibitors on Transthyretin Cardiac Amyloidosis and Heart Failure with Reduced Ejection Fraction

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Puerta de Hierro University Hospital 114
Not applicableUnknownNCT03098901
What this trial is testing

Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease

Who this might be right for
Cardiac TTR Amyloidosis
Kaplan Medical Center 100
Not applicableEnrolling By InvitationNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableUnknownNCT05896904
What this trial is testing

Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure
Aarhus University Hospital Skejby 100
Large-scale testing (Phase 3)Not Yet RecruitingNCT07789483
What this trial is testing

An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of ALXN2220 in Adults With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Alexion Pharmaceuticals, Inc. 1,180
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Testing effectiveness (Phase 2)UnknownNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Large-scale testing (Phase 3)Enrolling By InvitationNCT05667493
What this trial is testing

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
Ionis Pharmaceuticals, Inc. 1,400
Testing effectiveness (Phase 2)WithdrawnNCT04843020
What this trial is testing

ION-682884 in Patients With TTR Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiopathy
Brigham and Women's Hospital
Testing effectiveness (Phase 2)Study completedNCT01855360
What this trial is testing

Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Amyloidosis; Heart (Manifestation)Senile Cardiac Amyloidosis
Brigham and Women's Hospital 40
Not applicableEnrolling By InvitationNCT07398950
What this trial is testing

Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
ATTR Amyloidosis With CardiomyopathyHeart Failure
Yale University 150
Not applicableStudy completedNCT06372301
What this trial is testing

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid CardiomyopathyAortic Stenosis
Steen Hvitfeldt Poulsen 15
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableNot Yet RecruitingNCT07557147
What this trial is testing

Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Bayer 60
Not applicableLooking for participantsNCT07358078
What this trial is testing

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 2,000
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
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