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Results for “Transthyretin Amyloidosis (ATTR) With Cardiomyopathy”

69 trials

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Showing 20 of 69 results

Large-scale testing (Phase 3)Looking for participantsNCT07207811
What this trial is testing

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S 1,280
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Testing effectiveness (Phase 2)Active Not RecruitingNCT03536767
What this trial is testing

Open-Label Study of AG10 in Patients with Cardiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
Eidos Therapeutics, a BridgeBio company 55
Not applicableUnknownNCT05896904
What this trial is testing

Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure
Aarhus University Hospital Skejby 100
Testing effectiveness (Phase 2)Looking for participantsNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Large-scale testing (Phase 3)Active Not RecruitingNCT06183931
What this trial is testing

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Alexion Pharmaceuticals, Inc. 1,181
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Not applicableNot Yet RecruitingNCT07398950
What this trial is testing

Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
ATTR Amyloidosis With CardiomyopathyHeart Failure
Yale University 150
Not applicableLooking for participantsNCT05098665
What this trial is testing

PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY

Who this might be right for
Cardiac Amyloidosis
Richmond Research Institute 320
Not applicableUnknownNCT05699044
What this trial is testing

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

Who this might be right for
Amyloid CardiomyopathyBlock, AV
Steen Hvitfeldt Poulsen 170
Large-scale testing (Phase 3)Study completedNCT00935012
What this trial is testing

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Who this might be right for
ATTR-CMTTR-CM
Pfizer 31
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT07213583
What this trial is testing

Study of Re-Treatment With ALXN2220 in Patients With ATTR-CM

Who this might be right for
Amyloid Transthyretin Cardiomyopathy
Neurimmune AG 35
Not applicableEnded earlyNCT06338839
What this trial is testing

Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy, Heart Failure With Preserved Ejection Fraction
AstraZeneca 1,770
Not applicableUnknownNCT04985734
What this trial is testing

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy

Who this might be right for
Amyloidosis CardiacAmyloid PolyneuropathyAmyloidosis+3 more
University Hospital, Antwerp 200
Not applicableUnknownNCT03098901
What this trial is testing

Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease

Who this might be right for
Cardiac TTR Amyloidosis
Kaplan Medical Center 100
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