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Results for “Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)”

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT04601051
What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableStudy completedNCT06073587
What this trial is testing

The CARDIO-TTRansform Scintigraphy Sub-study

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Ionis Pharmaceuticals, Inc. 163
Testing effectiveness (Phase 2)Active Not RecruitingNCT07213583
What this trial is testing

Study of Re-Treatment With ALXN2220 in Patients With ATTR-CM

Who this might be right for
Amyloid Transthyretin Cardiomyopathy
Neurimmune AG 35
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Early research (Phase 1)Ended earlyNCT03417830
What this trial is testing

Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

Who this might be right for
Amyloidosis
GlaxoSmithKline 2
Large-scale testing (Phase 3)Study completedNCT00935012
What this trial is testing

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Who this might be right for
ATTR-CMTTR-CM
Pfizer 31
Not applicableStudy completedNCT04108091
What this trial is testing

Vyndaqel Capsules Special Investigation (ATTR-CM)

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,214
Not applicableEnrolling By InvitationNCT07398950
What this trial is testing

Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
ATTR Amyloidosis With CardiomyopathyHeart Failure
Yale University 150
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Not applicableStudy completedNCT03842163
What this trial is testing

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 812
Not applicableLooking for participantsNCT07690436
What this trial is testing

Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
AstraZeneca 500
Not applicableStudy completedNCT06372301
What this trial is testing

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid CardiomyopathyAortic Stenosis
Steen Hvitfeldt Poulsen 15
Post-approval studies (Phase 4)Looking for participantsNCT07298044
What this trial is testing

Learn More About the Change in the Blood Levels of Transthyretin When Participants With Transthyretin Amyloidosis With Cardiomyopathy Switch From Tafamidis to Acoramidis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Bayer 50
Not applicableStudy completedNCT05139680
What this trial is testing

Examine the Clinical Effectiveness of Tafamidis in Patients With Mixed Phenotype Hereditary Transthyretin Amyloidosis

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv) Cardiomyopathy (CM), Mixed Phenotype
Pfizer 10
Large-scale testing (Phase 3)Active Not RecruitingNCT04988386
What this trial is testing

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Who this might be right for
Amyloid Cardiomyopathy, Transthyretin-Related
Eidos Therapeutics, a BridgeBio company 389
Post-approval studies (Phase 4)Study completedNCT04814186
What this trial is testing

Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Pfizer 53
Not applicableLooking for participantsNCT07791160
What this trial is testing

Study of Acoramidis in Patients With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Bayer 500
Not applicableEnded earlyNCT04424914
What this trial is testing

Global Prevalence of ATTR-CM in Participants With HFpEF

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure With Preserved Ejection Fraction
Pfizer 347
Large-scale testing (Phase 3)Looking for participantsNCT06128629
What this trial is testing

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics 1,200
Not applicableNot Yet RecruitingNCT07784712
What this trial is testing

Right Ventricular Septal Biopsy to Detect Cardiac Amyloidosis

Who this might be right for
ATTR-CM (Transthyretin Amyloid Cardiomyopathy)Heart Failure
Geisinger Clinic 70
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