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Results for “Transthyretin Amyloidosis Polyneuropathy”

104 trials

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Showing 20 of 104 results

Post-approval studies (Phase 4)Study completedNCT04828993
What this trial is testing

The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients

Who this might be right for
Transthyretin Amyloid Polyneuropathy (ATTR-PN)
Pfizer 15
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Testing effectiveness (Phase 2)Active Not RecruitingNCT03536767
What this trial is testing

Open-Label Study of AG10 in Patients with Cardiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
Eidos Therapeutics, a BridgeBio company 55
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Not applicableWithdrawnNCT02713880
What this trial is testing

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Who this might be right for
Transthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin Amyloid Cardiopathy
CENTOGENE GmbH Rostock
Not applicableStudy completedNCT04201418
What this trial is testing

Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Who this might be right for
Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy
Alnylam Pharmaceuticals 67
Testing effectiveness (Phase 2)Looking for participantsNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Not applicableStudy completedNCT03322319
What this trial is testing

Frequency of Cardiac Amyloidosis in the Caribbean's. (TEAM Amylose)

Who this might be right for
Left Ventricular Hypertrophy
University Hospital Center of Martinique 175
Large-scale testing (Phase 3)Study completedNCT01737398
What this trial is testing

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Who this might be right for
FAPFamilial Amyloid PolyneuropathyTTR+2 more
Ionis Pharmaceuticals, Inc. 173
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Large-scale testing (Phase 3)Study completedNCT00294671
What this trial is testing

The Effect of Diflunisal on Familial Amyloidosis

Who this might be right for
Familial Amyloid PolyneuropathyFamilial Amyloidosis
Boston University 130
Not applicableActive Not RecruitingNCT05873868
What this trial is testing

Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran

Who this might be right for
Transthyretin AmyloidosisAmyloidosis, Hereditary
Rennes University Hospital 20
Not applicableLooking for participantsNCT06887283
What this trial is testing

Essen Amyloidosis Registry

Who this might be right for
Amyloidosis; SystemicAmyloidosis Cardiac
University Hospital, Essen 400
Large-scale testing (Phase 3)WithdrawnNCT04418024
What this trial is testing

Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid Polyneurophathy

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Eidos Therapeutics, a BridgeBio company
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Not applicableStudy completedNCT05560555
What this trial is testing

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy
Pfizer 5
Not applicableUnknownNCT05699044
What this trial is testing

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

Who this might be right for
Amyloid CardiomyopathyBlock, AV
Steen Hvitfeldt Poulsen 170
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