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Results for “Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy”

37 trials

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Showing 20 of 37 results

Not applicableActive Not RecruitingNCT04869631
What this trial is testing

Screening for Amyloidosis Before Aortic Valve Elective Replacement

Who this might be right for
AmyloidosisAortic Valve Stenosis
Charite University, Berlin, Germany 1,000
Large-scale testing (Phase 3)Study completedNCT03862807
What this trial is testing

Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant

Who this might be right for
Amyloidosis, FamilialTransthyretin Amyloidosis
Alnylam Pharmaceuticals 24
Not applicableStudy completedNCT05311488
What this trial is testing

Early Detection of Neuropathy in ATTRv

Who this might be right for
Hereditary Amyloidosis, Transthyretin-Related
University of Pennsylvania 47
Not applicableWithdrawnNCT02713880
What this trial is testing

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Who this might be right for
Transthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin Amyloid Cardiopathy
CENTOGENE GmbH Rostock
Not applicableNot Yet RecruitingNCT06921408
What this trial is testing

Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

Who this might be right for
Cardiac AmyloidosisTransthyretin Amyloidosis
University Hospital, Lille 57
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableLooking for participantsNCT06465810
What this trial is testing

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Who this might be right for
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca 1,850
Not applicableStudy completedNCT06365593
What this trial is testing

HATTR Polyneuropathy in Russia

Who this might be right for
Hereditary Transthyretin Amyloidosis
AstraZeneca 100
Not applicableLooking for participantsNCT07196839
What this trial is testing

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
University of Texas Southwestern Medical Center 50
Not applicableStudy completedNCT03431896
What this trial is testing

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

Who this might be right for
AmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more
The Cleveland Clinic 37
Early research (Phase 1)Study completedNCT03294707
What this trial is testing

Single and Multiple Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of AG10

Who this might be right for
Amyloid Cardiomyopathy, Transthyretin-Related
Eidos Therapeutics, a BridgeBio company 56
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Post-approval studies (Phase 4)Looking for participantsNCT07695701
What this trial is testing

Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)AmyloidosisAmyloid Cardiomyopathy+1 more
Eidos Therapeutics, a BridgeBio company 150
Not applicableUnknownNCT06714019
What this trial is testing

PL_GNT01_ISR_Grant 53234273

Who this might be right for
Transthyretin Cardiomyopathy (TTR-CM)Transthyretin (TTR) Amyloid CardiomyopathyTransthyretin Amyloidosis
National Institute of Cardiology, Warsaw, Poland 100
Large-scale testing (Phase 3)Study completedNCT03759379
What this trial is testing

HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

Who this might be right for
Amyloidosis, HereditaryTransthyretin Amyloidosis
Alnylam Pharmaceuticals 164
Not applicableEnrolling By InvitationNCT07238426
What this trial is testing

ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey

Who this might be right for
Cardiac AmyloidosisTransthyretin Amyloidosis
Kotyora Family Medicine Health Management and Education Association 800
Large-scale testing (Phase 3)Looking for participantsNCT06563895
What this trial is testing

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more
Eidos Therapeutics, a BridgeBio company 587
Not applicableStudy completedNCT03812172
What this trial is testing

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations

Who this might be right for
Amyloid Cardiomyopathy, Transthyretin-Related
Mathew S. Maurer, MD 646
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