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Results for “Transthyretin-type Cardiac Amyloidosis”

44 trials

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Showing 20 of 44 results

Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Large-scale testing (Phase 3)Active Not RecruitingNCT06183931
What this trial is testing

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Alexion Pharmaceuticals, Inc. 1,181
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Not applicableLooking for participantsNCT06887283
What this trial is testing

Essen Amyloidosis Registry

Who this might be right for
Amyloidosis; SystemicAmyloidosis Cardiac
University Hospital, Essen 400
Not applicableUnknownNCT05814380
What this trial is testing

The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.

Who this might be right for
Transthyretin Amyloidosis
Katarzyna Holcman 100
Large-scale testing (Phase 3)Study completedNCT00935012
What this trial is testing

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Who this might be right for
ATTR-CMTTR-CM
Pfizer 31
Not applicableLooking for participantsNCT06291805
What this trial is testing

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more
Steen Hvitfeldt Poulsen 120
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Not applicableNot Yet RecruitingNCT06499064
What this trial is testing

EOSS-ATTR Study (eHealth Based Operative Support System in ATTR-CM)

Who this might be right for
Heart FailureAmyloid CardiomyopathyATTR Amyloidosis Wild Type+1 more
Hospital Universitari de Bellvitge 50
Not applicableUnknownNCT02260466
What this trial is testing

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.

Who this might be right for
Heart DiseaseAgingAmyloidosis+1 more
French Cardiology Society 186
Not applicableEnrolling By InvitationNCT06412432
What this trial is testing

Exercise Training and Rehabilitation In Cardiac Amyloidosis

Who this might be right for
Cardiac Amyloidosis
Federico II University 34
Not applicableLooking for participantsNCT07314268
What this trial is testing

ATTR Amyloid Cardiomyopathy: Characterization of Extracellular Vesicles as Potential Disease Stratifiers and Prognostic Biomarkers

Who this might be right for
Wild-type ATTR AmyloidosisAmyloidosis CardiacAmyloidosis, Hereditary+1 more
University of Sao Paulo General Hospital 70
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 35
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Testing effectiveness (Phase 2)WithdrawnNCT02627820
What this trial is testing

The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart

Who this might be right for
Amyloidosis
Brigham and Women's Hospital
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