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Results for “Transthyretin-type Cardiac Amyloidosis”

44 trials

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Showing 20 of 44 results

Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Large-scale testing (Phase 3)Active Not RecruitingNCT06183931
What this trial is testing

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Alexion Pharmaceuticals, Inc. 1,181
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Testing effectiveness (Phase 2)Ended earlyNCT03702829
What this trial is testing

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Who this might be right for
Amyloidosis
Brigham and Women's Hospital 31
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Not applicableStudy completedNCT03431896
What this trial is testing

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

Who this might be right for
AmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more
The Cleveland Clinic 37
Very early researchStudy completedNCT05023889
What this trial is testing

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Who this might be right for
PolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more
Austin Neuromuscular Center 10
Not applicableStudy completedNCT06261216
What this trial is testing

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Amyloid CardiomyopathyWild Type ATTR Amyloidosis
Medical University of Graz 180
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Not applicableStudy completedNCT03966105
What this trial is testing

Prevalence of Wild Type ATTR

Who this might be right for
Wild-type Transthyretin Amyloidosis
Oncology Institute of Southern Switzerland 94
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableStudy completedNCT03923920
What this trial is testing

Screening for Systemic Amyloidosis Via the Ligamentum Flavum

Who this might be right for
AmyloidAmyloidosisSpinal Stenosis+2 more
The Cleveland Clinic 200
Not applicableStudy completedNCT03996382
What this trial is testing

Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome

Who this might be right for
Amyloidosis CardiacCarpal Tunnel Syndrome
Aarhus University Hospital Skejby 120
Not applicableLooking for participantsNCT06836011
What this trial is testing

Study on Atrioventricular Regurgitation in Transthyretin Amyloid Cardiomyopathy: Definition, Prevalence, and Prognostic Impact.

Who this might be right for
ATTR Amyloidosis With CardiomyopathyATTR-CMATTR Amyloidosis Wild Type+2 more
Medical University of Vienna 600
Not applicableLooking for participantsNCT06465810
What this trial is testing

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Who this might be right for
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca 1,850
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,250
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
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