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Results for “Transthyretin-type Cardiac Amyloidosis”

46 trials

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Showing 20 of 46 results

Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Early research (Phase 1)Study completedNCT05201911
What this trial is testing

Characterize the Biodistribution of 124I-Labeled AT-03 in Patients With Systemic Amyloidosis

Who this might be right for
Amyloidosis; Systemic
Attralus, Inc. 13
Not applicableUnknownNCT04563286
What this trial is testing

Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloidosis
University of Messina 250
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Not applicableStudy completedNCT06372301
What this trial is testing

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid CardiomyopathyAortic Stenosis
Steen Hvitfeldt Poulsen 15
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Not applicableLooking for participantsNCT06291805
What this trial is testing

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more
Steen Hvitfeldt Poulsen 120
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Not applicableStudy completedNCT03431896
What this trial is testing

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

Who this might be right for
AmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more
The Cleveland Clinic 37
Not applicableStudy completedNCT03886155
What this trial is testing

Cardiac Amyloidosis Screening at Trigger Finger Release

Who this might be right for
AmyloidosisTrigger FingerTransthyretin Amyloidosis+1 more
The Cleveland Clinic 107
Not applicableLooking for participantsNCT06251778
What this trial is testing

NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis

Who this might be right for
AmyloidosisAmyloidosis CardiacATTR Amyloidosis Wild Type
Paolo Milani 200
Not applicableLooking for participantsNCT07766135
What this trial is testing

Liver and Coagulation Disorders in Cardiac Transthyretin Amyloidosis

Who this might be right for
Transthyretin (TTR) Amyloid CardiomyopathyCardiac AmyloidosisCardiomyopathies+2 more
University of Messina 70
Not applicableStudy completedNCT06261216
What this trial is testing

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Amyloid CardiomyopathyWild Type ATTR Amyloidosis
Medical University of Graz 180
Testing effectiveness (Phase 2)WithdrawnNCT02627820
What this trial is testing

The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart

Who this might be right for
Amyloidosis
Brigham and Women's Hospital
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableUnknownNCT05814380
What this trial is testing

The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.

Who this might be right for
Transthyretin Amyloidosis
Katarzyna Holcman 100
Large-scale testing (Phase 3)Study completedNCT00935012
What this trial is testing

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Who this might be right for
ATTR-CMTTR-CM
Pfizer 31
Early research (Phase 1)Study completedNCT04601051
What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
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