Not applicableStudy completedNCT03105700What this trial is testingLow Frequency TMS for Depression in EpilepsyWho this might be right forEpilepsyDepressions, Refractory Dartmouth-Hitchcock Medical Center 15
Post-approval studies (Phase 4)Study completedNCT00305565What this trial is testingStudy Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different DosesWho this might be right forDepression Cyberonics, Inc. 331
Post-approval studies (Phase 4)Study completedNCT02134808What this trial is testingCreatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive DisorderWho this might be right forMajor Depressive Disorder Perry Renshaw 71
Testing effectiveness (Phase 2)WithdrawnNCT05438758What this trial is testingRepeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension StudyWho this might be right forTreatment Resistant Major Depressive Disorder Zylorion Health
Not applicableUnknownNCT05716555What this trial is testingDeep Brain Stimulation for Treatment Resistant DepressionWho this might be right forDepressive Disorder, Major Second Affiliated Hospital, School of Medicine, Zhejiang University 2
Large-scale testing (Phase 3)Study completedNCT02125799What this trial is testingAccelerated rTMS for Treatment-Resistant Major DepressionWho this might be right forMajor Depressive Disorder Douglas Mental Health University Institute 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04433858What this trial is testingAn Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)Who this might be right forTreatment Resistant Depression Sheppard Pratt Health System 27
Not applicableNot Yet RecruitingNCT06748950What this trial is testingKetogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic ProfilingWho this might be right forSchizophreniaSchizophrenia and Related DisordersBipolar Disorder+7 more Stanford University 120
Post-approval studies (Phase 4)Study completedNCT03149991What this trial is testingBrexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)Who this might be right forDepression Massachusetts General Hospital 51
Not applicableStudy completedNCT00186056What this trial is testingMifepristone in Refractory DepressionWho this might be right forDepression Stanford University 31
Not applicableStudy completedNCT06331572What this trial is testingExploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent DepressionWho this might be right forPsychiatric DisorderMajor Depressive DisorderMetabolic Disorder First Affiliated Hospital of Chongqing Medical University 162
Not applicableWithdrawnNCT02238730What this trial is testingUltrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive TherapyWho this might be right forDepressionDepressive DisorderTreatment Resistant Depressive Disorder+2 more Kaiser Permanente
Not applicableUnknownNCT02219867What this trial is testingKetamine Infusions for Major Depression DisorderWho this might be right forDepressive Disorder, Major Sheba Medical Center 10
Testing effectiveness (Phase 2)Looking for participantsNCT05710237What this trial is testingDoes Psilocybin Require Psychedelic Effects to Treat Depression?Who this might be right forTreatment-resistant Depression Centre for Addiction and Mental Health 60
Post-approval studies (Phase 4)Study completedNCT04504175What this trial is testingKetamine for Older Adults PilotWho this might be right forTreatment Resistant DepressionRefractory DepressionTherapy-Resistant Depression+2 more Washington University School of Medicine 25
Not applicableUnknownNCT05355142What this trial is testingAn Intervention Study of Anhedonia and Pain Empathy in DepressionWho this might be right forTreatment Resistant DepressionProblem Management PlusEvent-Related Potentials Anhui Medical University 66
Not applicableStudy completedNCT06730841What this trial is testingDose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant DepressionWho this might be right forTreatment Resistant DepressionMajor Depressive Disorder University of California, San Diego 3
Not applicableStudy completedNCT01944644What this trial is testingLow Field Magnetic Stimulation for Treatment Resistant DepressionWho this might be right forTreatment Resistant Depression Weill Medical College of Cornell University 66
Early research (Phase 1)Looking for participantsNCT06096207What this trial is testingDBS for DepressionWho this might be right forTreatment Resistant Depression Northwell Health 20
Early research (Phase 1)Study completedNCT00437385What this trial is testingEvaluation of Three Continuation Therapies After ECT Concerning Efficacy and Cognition in Severly Depressed PatientsWho this might be right forDepressionMajor Depression Charite University, Berlin, Germany 90