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Results for “Treatment naïve”

944 trials

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Showing 20 of 944 results

Testing effectiveness (Phase 2)WithdrawnNCT01933061
What this trial is testing

Study to Determine Efficacy and Safety of CC-486 With Nab-Paclitaxel Versus Nab-Paclitaxel in Patients With Chemotherapy naïve Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Celgene Corporation
Testing effectiveness (Phase 2)Looking for participantsNCT04165070
What this trial is testing

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 450
Post-approval studies (Phase 4)Study completedNCT01528254
What this trial is testing

VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus

Who this might be right for
Type 2 Diabetes Mellitus
Novartis Pharmaceuticals 2,004
Not applicableNot Yet RecruitingNCT07236931
What this trial is testing

Clinical Study of Selinexor-Based Chemotherapy With Minimal or No Cytotoxic Agents in Treatment-Naïve AML Patients Unsuitable for Intensive Therapy: Focusing on Rapid Reduction of Blast Cells

Who this might be right for
AML (Acute Myeloid Leukemia)
Donghua Zhang 71
Large-scale testing (Phase 3)Study completedNCT02105467
What this trial is testing

Study of Efficacy and Safety of Grazoprevir (MK-5172)/Elbasvir (MK-8742) Combination Regimen for Treatment-Naïve Participants With Chronic Hepatitis C Virus Genotypes 1, 4, and 6 (MK-5172-060)

Who this might be right for
Chronic Hepatitis C Virus
Merck Sharp & Dohme LLC 421
Testing effectiveness (Phase 2)Study completedNCT03007732
What this trial is testing

Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT

Who this might be right for
Prostatic Neoplasms
David Oh 23
Large-scale testing (Phase 3)Study completedNCT02855684
What this trial is testing

Comparison of the Efficacy and Safety of a New Formulation of Insulin Glargine With Lantus in Patients With Type 2 Diabetes Insufficiently Controlled With Non-insulin Antidiabetic Therapy

Who this might be right for
Type 2 Diabetes Mellitus
Sanofi 604
Large-scale testing (Phase 3)Study completedNCT03178084
What this trial is testing

Effects of Maraviroc vs. Efavirenz on CD4/CD8 Ratio

Who this might be right for
HIV/AIDS
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal 721
Testing effectiveness (Phase 2)Active Not RecruitingNCT05309421
What this trial is testing

A Single Arm Trial Evaluating the Efficacy and Safety of EVX-01 in Combination With Pembrolizumab in Adults With Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma Stage IVUnresectable Melanoma
Evaxion Biotech A/S 17
Large-scale testing (Phase 3)Active Not RecruitingNCT03711032
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
Merck Sharp & Dohme LLC 1,397
Testing effectiveness (Phase 2)Active Not RecruitingNCT04216316
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer

Who this might be right for
Lung Non-Small Cell Squamous CarcinomaStage IV Lung Cancer AJCC v8
National Cancer Institute (NCI) 12
Testing effectiveness (Phase 2)Ended earlyNCT02500927
What this trial is testing

ASP8273 in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-Naïve Patients With Non-Small Cell Lung Cancer Harboring EGFR Mutations

Who this might be right for
EGFR-TKI-naïve Patients With NSCLC Harboring EGFR Activating Mutations
Astellas Pharma Inc 31
Not applicableStudy completedNCT02605642
What this trial is testing

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade

Who this might be right for
Rheumatoid DiseasesRheumatoid ArthritisAnkylosing Spondylitis+1 more
Pfizer 351
Large-scale testing (Phase 3)Looking for participantsNCT07221669
What this trial is testing

Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Who this might be right for
Muscular Atrophy, Spinal
Biogen 30
Post-approval studies (Phase 4)Study completedNCT01512979
What this trial is testing

Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes

Who this might be right for
Diabetes Mellitus, Type 2
Boehringer Ingelheim 316
Not applicableStudy completedNCT01054742
What this trial is testing

Observational Study of Patients With Chronic Hepatitis C Virus (HCV) Infected With HCV Genotype 1 Low Virus Load (LVL 1) and Effect of PegIntron Plus Rebetol Treatment (Study P04793 Part 2)

Who this might be right for
Hepatitis C
Merck Sharp & Dohme LLC 2
Not applicableStudy completedNCT04988178
What this trial is testing

Analysis of naïve Patients With Age-related Macular Degeneration Neovascular Type and Treated With Ranibizumab (Lucentis®) in Treat-and-extend at the CHU Brugmann.

Who this might be right for
Macular Degeneration
Brugmann University Hospital 34
Large-scale testing (Phase 3)Ended earlyNCT00745823
What this trial is testing

Determine the Safety and Efficacy of Once Daily Raltegravir Compared to Twice Daily Raltegravir (MK-0518-071)

Who this might be right for
HIV
Merck Sharp & Dohme LLC 775
Post-approval studies (Phase 4)Study completedNCT00237146
What this trial is testing

Study to Evaluate Zoledronic Acid on Quality of Life and Skeletal-related Events as Adjuvant Treatment in Patients With Hormone-naïve Prostate Cancer and Bone Metastasis Who Have Undergone Orchiectomy

Who this might be right for
Prostate Cancer
Novartis Pharmaceuticals 38
Large-scale testing (Phase 3)Study completedNCT01422876
What this trial is testing

Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients

Who this might be right for
Diabetes Mellitus, Type 2
Boehringer Ingelheim 1,405
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