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Results for “Treatment-Naive B Cell Malignancies”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)UnknownNCT02825836
What this trial is testing

Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects

Who this might be right for
Relapsed/Refractory B Cell MalignanciesMantle Cell Lymphoma and Diffuse Large B Cell LymphomaChronic Lymphocytic Leukemia+2 more
Telios Pharma, Inc. 130
Testing effectiveness (Phase 2)Active Not RecruitingNCT02514083
What this trial is testing

A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
National Heart, Lung, and Blood Institute (NHLBI) 29
Early research (Phase 1)Study completedNCT03447808
What this trial is testing

Daratumumab and Ibrutinib in Treating Patients With Symptomatic Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
Jennifer Woyach 15
Testing effectiveness (Phase 2)Study completedNCT04508647
What this trial is testing

Ublituximab Followed by Response-driven Addition of Umbralisib for Treatment-naive Follicular or Marginal Zone Lymphoma

Who this might be right for
Marginal Zone LymphomaFollicular Lymphoma
University of Colorado, Denver 4
Early research (Phase 1)UnknownNCT01976520
What this trial is testing

Vaccine Therapy for Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
XEME Biopharma Inc. 30
Large-scale testing (Phase 3)Looking for participantsNCT05018520
What this trial is testing

The Safety and Effectiveness of 4R-CHOP+4R vs 6R-CHOP+2R in Newly Diagnosed Patients With DLBCL in Low Risk

Who this might be right for
Diffuse Large B Cell Lymphoma
Ruijin Hospital 640
Testing effectiveness (Phase 2)Looking for participantsNCT06530511
What this trial is testing

Polatuzumab, Rituximab and Orelabrutinib Combination Regimen (PRO) in the Treatment of Elderly Frail Patients with Treatment-naive Non-GCB DLBCL

Who this might be right for
Diffuse Large B Cell Lymphoma
Affiliated Hospital of Nantong University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04460248
What this trial is testing

Zanubrutinib, Lenalidomide and Rituximab (ZR2) in Elderly Treatment-naive Patients With Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large B Cell Lymphoma
Ruijin Hospital 40
Testing effectiveness (Phase 2)Study completedNCT02013817
What this trial is testing

CHAIROS Study A Study of MabThera/Rituxan (Rituximab) Maintenance Therapy in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Naive to Chemotherapy

Who this might be right for
Lymphocytic Leukemia, Chronic
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)UnknownNCT05940064
What this trial is testing

Prospective Clinical Study of ZPR Regimen in Elderly Treatment-naive Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B Cell Lymphoma
Peng Liu 30
Testing effectiveness (Phase 2)Looking for participantsNCT05336812
What this trial is testing

Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Ohio State University Comprehensive Cancer Center 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07508995
What this trial is testing

Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
M.D. Anderson Cancer Center 40
Not applicableLooking for participantsNCT05950997
What this trial is testing

A Single Arm Study of Acalabrutinib Conbimed With Obinutuzumab in Chinese Patients With Previously Untreated CLL

Who this might be right for
Chronic Lymphocytic Leukemia
The First Affiliated Hospital with Nanjing Medical University 89
Testing effectiveness (Phase 2)Active Not RecruitingNCT03620903
What this trial is testing

Efficacy of First Line B-RI for Treatment Naive Waldenström's Macroglobulinemia

Who this might be right for
Waldenstrom Macroglobulinemia
Christian Buske 53
Testing effectiveness (Phase 2)UnknownNCT00258336
What this trial is testing

Rituximab, Vaccine Therapy, and GM-CSF in Treating Patients With Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma
Favrille 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT04505254
What this trial is testing

Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Study completedNCT02910583
What this trial is testing

Ibrutinib Plus Venetoclax in Subjects With Treatment-naive Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma (CLL/SLL)

Who this might be right for
LeukemiaChronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Pharmacyclics LLC. 323
Not applicableNo Longer AvailableNCT04052854
What this trial is testing

A Single-Arm, Expanded Access Study of Zanubrutinib in Participants With B-cell Malignancies

Who this might be right for
Waldenström Macroglobulinemia
BeiGene
Testing effectiveness (Phase 2)Looking for participantsNCT03980002
What this trial is testing

A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLL

Who this might be right for
Chronic Lymphocytic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 50
Not applicableUnknownNCT05809180
What this trial is testing

Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients

Who this might be right for
Diffuse Large B Cell Lymphoma
The First Affiliated Hospital of Soochow University 35
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