Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Treatment-Resistant Major Depressive Disorder”

377 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 377 results

Testing effectiveness (Phase 2)WithdrawnNCT05381974
What this trial is testing

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Treatment Resistant MDD

Who this might be right for
Treatment-Resistant Major Depressive Disorder
Massachusetts General Hospital
Testing effectiveness (Phase 2)WithdrawnNCT05710887
What this trial is testing

N2O for Acute Suicidality and Depression in the ED

Who this might be right for
Suicidal IdeationMajor Depressive DisorderTreatment Resistant Depression
University of Chicago
Testing effectiveness (Phase 2)Ended earlyNCT02882711
What this trial is testing

The UTHealth Ketamine Project

Who this might be right for
Treatment Resistant DepressionMajor Depressive DisorderBipolar Disorder
The University of Texas Health Science Center, Houston 10
Early research (Phase 1)WithdrawnNCT03833063
What this trial is testing

Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression

Who this might be right for
Major Depressive DisorderMajor Depressive EpisodeTreatment Resistant Depression
Helse Stavanger HF
Post-approval studies (Phase 4)Ended earlyNCT00296686
What this trial is testing

Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression

Who this might be right for
Major Depression
New York State Psychiatric Institute 31
Not applicableActive Not RecruitingNCT05172271
What this trial is testing

Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

Who this might be right for
Major Depressive DisorderBipolar DisorderUnipolar Major Depression
National Institute of Mental Health (NIMH) 8
Not applicableStudy completedNCT03977038
What this trial is testing

Investigation of the Effects of Repetitive Transcranial Magnetic Stimulation on Cognition in Depression

Who this might be right for
Major Depressive DisorderTreatment Resistant Depression
Sunnybrook Health Sciences Centre 25
Testing effectiveness (Phase 2)Study completedNCT01234558
What this trial is testing

Single IV Dose of GLYX-13 in Patients With Treatment-Resistant Depression

Who this might be right for
Major Depressive Disorder
Naurex, Inc, an affiliate of Allergan plc 115
Testing effectiveness (Phase 2)Study completedNCT03932825
What this trial is testing

Nitrous Oxide for Major Depressive Disorder

Who this might be right for
Depressive DisorderMajor Depressive DisorderTreatment Resistant Depression+2 more
Lingjiang Li 44
Not applicableLooking for participantsNCT07264452
What this trial is testing

Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst Stimulation in Patients With Treatment-Resistant Depression

Who this might be right for
Treatment Resistant Depression (TRD)Transcranial Magnetic StimulationAccelerated Protocol+3 more
Ataturk University 60
Not applicableUnknownNCT05422417
What this trial is testing

Dorsomedial Prefrontal Neuromodulation in Treatment-resistant Depression

Who this might be right for
Treatment-resistant DepressionMajor Depressive Disorder
Taipei Veterans General Hospital, Taiwan 75
Large-scale testing (Phase 3)Study completedNCT03435744
What this trial is testing

Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Pakistan Institute of Living and Learning 150
Not applicableLooking for participantsNCT07528014
What this trial is testing

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Who this might be right for
Depressed Mood
Salma Health, Inc. 5,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07373535
What this trial is testing

Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy

Who this might be right for
Treatment-Resistant Major Depressive Disorder
Kyle Greenway 16
Not applicableStudy completedNCT01431001
What this trial is testing

Pilot Study in Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depression

Who this might be right for
Major Depressive Disorder
Cervel Neurotech, Inc. 40
Not applicableLooking for participantsNCT06396312
What this trial is testing

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression

Who this might be right for
Depressive; Disorder, Major, Single Episode, Major, With Psychotic SymptomsDepressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms)Depressive Disorder, Major, Recurrent, With Psychotic Symptoms+4 more
Max-Planck-Institute of Psychiatry
Not applicableEnded earlyNCT06431386
What this trial is testing

Behavioural Activation Therapy and Esketamine for Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-ResistantDepressive Disorder, MajorBipolar Disorder
The Royal's Institute of Mental Health Research 6
Not applicableNot Yet RecruitingNCT07376018
What this trial is testing

Ketogenic Diet and Neuromodulation in Treatment Resistant Depression

Who this might be right for
Major Depressive Disorder (MDD)Treatment Resistant Depression (TRD)
Sunnybrook Health Sciences Centre 60
Not applicableUnknownNCT06095778
What this trial is testing

RTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS

Who this might be right for
MDDMajor Depressive DisorderTreatment Resistant Depression
Changping Laboratory 100
Not applicableStudy completedNCT01983904
What this trial is testing

DBS for Treatment Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-Resistant
University of Calgary 22
Next Page
130