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Results for “Trop2”

106 trials

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Showing 20 of 106 results

Testing effectiveness (Phase 2)Looking for participantsNCT07623577
What this trial is testing

Sac-TMT Combined With Bevacizumab in TNBC With Brain Metastases

Who this might be right for
TNBCBrain Metastasis
Fudan University 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07778368
What this trial is testing

A Multicenter, Prospective, Phase II Study of TROP-2 ADC in Combination With Toripalimab for Resectable Locally Advanced Oral Squamous Cell Carcinoma

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)
Shanghai East Hospital 20
Early research (Phase 1)Active Not RecruitingNCT06358430
What this trial is testing

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Who this might be right for
Colorectal CancerMinimal Residual Disease
M.D. Anderson Cancer Center 10
Early research (Phase 1)Looking for participantsNCT07067567
What this trial is testing

AK146D1 for Injection in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Akeso 200
Testing effectiveness (Phase 2)Looking for participantsNCT06235216
What this trial is testing

Sacituzumab govitEcan in THYroid Cancers

Who this might be right for
Differentiated Thyroid CancerAnaplastic Thyroid Cancer
Grupo Espanol de Tumores Neuroendocrinos 42
Not applicableLooking for participantsNCT07046455
What this trial is testing

Trop-2 Targeted PET Probes in Advanced TNBC

Who this might be right for
TNBC - Triple-Negative Breast Cancer
Peking University Cancer Hospital & Institute 20
Early research (Phase 1)Not Yet RecruitingNCT07674615
What this trial is testing

IMMU-132 in TROP-2 Overexpressed Advanced and Relapsed Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerFallopian Tube CancersPrimary+1 more
Shanghai Gynecologic Oncology Group 19
Not applicableLooking for participantsNCT07251868
What this trial is testing

Evaluation of Trop-2 ADC in Breast Cancer Patients With Brain Metastases: A Real-World Study

Who this might be right for
Breast CancerBrain Metastases From Breast CancerTrop2
Peking University Cancer Hospital & Institute 100
Testing effectiveness (Phase 2)Looking for participantsNCT06329869
What this trial is testing

Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
National Taiwan University Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT07088211
What this trial is testing

Sacituzumab Tirumotecan and Toripalimab in the First-line Treatment of HNSCC

Who this might be right for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 39
Not applicableEnded earlyNCT06465017
What this trial is testing

ImmunoPET Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) in Thyroid Cancer

Who this might be right for
TumorSolid TumorThyroid Cancer+1 more
The First Affiliated Hospital of Xiamen University 149
Not applicableLooking for participantsNCT07794813
What this trial is testing

Trop2-targeting NIR-II Molecular Probe for Precision Diagnosis of Oral Cancer

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Diagnosis
Yunnan Cancer Hospital 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07800507
What this trial is testing

Trop2-Targeted Near-Infrared Fluorescence Imaging-Guided Precise Resection of Non-Muscle Invasive Bladder Cancer

Who this might be right for
NMIBC
Yunnan Cancer Hospital 30
Not applicableLooking for participantsNCT07177482
What this trial is testing

ImmunoPET Targeting Trophoblast Cell-surface Antigen 2 (Trop-2) in Craniopharyngioma Patients

Who this might be right for
Craniopharyngioma
Deling Li 20
Large-scale testing (Phase 3)Looking for participantsNCT06952504
What this trial is testing

Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Who this might be right for
Endometrial Cancer
Merck Sharp & Dohme LLC 1,123
Testing effectiveness (Phase 2)Active Not RecruitingNCT05327530
What this trial is testing

The Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

Who this might be right for
Locally Advanced or Metastatic Urothelial Carcinoma
EMD Serono Research & Development Institute, Inc. 256
Testing effectiveness (Phase 2)Looking for participantsNCT06953089
What this trial is testing

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumors
DualityBio Inc. 450
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940325
What this trial is testing

Datopotamab Deruxtecan (Dato-DXd, DS-1062a) in Advanced and/or Unresectable Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Lung CancerAdvanced Non Small Cell Lung CancerUnresectable Non-small Lung Cancer
Gustave Roussy, Cancer Campus, Grand Paris 100
Not applicableLooking for participantsNCT07026110
What this trial is testing

Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer

Who this might be right for
Lung CancerLung DiseasesLung Neoplasms+2 more
RenJi Hospital 100
Testing effectiveness (Phase 2)Looking for participantsNCT06878625
What this trial is testing

A Multicenter, Prospective, Cohort Study of Trop-2 ADC Combination Therapy for Advanced Triple-negative Breast Cancer

Who this might be right for
Evaluating the Efficacy of Trop-2 ADC Combination Therapy in Advanced Triple-Negative Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 138
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