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Results for “Trop2”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Looking for participantsNCT06953089
What this trial is testing

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumors
DualityBio Inc. 492
Not applicableLooking for participantsNCT06696326
What this trial is testing

Study Evaluating the Diagnostic Value of 68Ga-MY6349 PET/CT for Prostate Cancer

Who this might be right for
Positron-Emission Tomography(PET)Prostate CancerTrophoblast Cell Surface Antigen 2
The First Affiliated Hospital of Xiamen University 100
Early research (Phase 1)Ended earlyNCT04601285
What this trial is testing

A Phase I Study of JS108 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd. 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07411599
What this trial is testing

Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")

Who this might be right for
Colorectal CancerPeritoneal MetastasesCarcinomatosis
M.D. Anderson Cancer Center 28
Not applicableLooking for participantsNCT07046702
What this trial is testing

68Ga-MY6349 PET/CT in Solid Tumors

Who this might be right for
Solid TumorTrop2PET/CT
The First Affiliated Hospital of Xiamen University 300
Testing effectiveness (Phase 2)Looking for participantsNCT06902389
What this trial is testing

A Clinical Study of Multi-target Hi-TCR-T Cells in the Treatment of Advanced Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular Carcinoma (HCC)
Eastern Hepatobiliary Surgery Hospital 30
Not applicableLooking for participantsNCT06602037
What this trial is testing

ImmunoPET Imaging of Pancreatic Cancer

Who this might be right for
Neoplasms Pancreatic
RenJi Hospital 90
Early research (Phase 1)Looking for participantsNCT06066424
What this trial is testing

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Who this might be right for
Solid Tumors
M.D. Anderson Cancer Center 54
Not applicableLooking for participantsNCT07026110
What this trial is testing

Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer

Who this might be right for
Lung CancerLung DiseasesLung Neoplasms+2 more
RenJi Hospital 100
Testing effectiveness (Phase 2)Looking for participantsNCT06851299
What this trial is testing

The Clinical Study of the Efficacy and Safety of Trop2-ADC Monotherapy or Combination Immunotherapy Strategy in the Treatment of Advanced Triple-negative Breast Cancer.

Who this might be right for
Metastatic Triple-negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 60
Not applicableActive Not RecruitingNCT07314255
What this trial is testing

The Role of Trop2 in Radioactive Iodine-131 Therapy Sensitivity in Papillary Thyroid Carcinoma

Who this might be right for
PTCI-131Trop2
Jiangxi Provincial Cancer Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT06878625
What this trial is testing

A Multicenter, Prospective, Cohort Study of Trop-2 ADC Combination Therapy for Advanced Triple-negative Breast Cancer

Who this might be right for
Evaluating the Efficacy of Trop-2 ADC Combination Therapy in Advanced Triple-Negative Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 138
Early research (Phase 1)WithdrawnNCT05060276
What this trial is testing

Study to Assess an Anti-Trop2 Antibody Drug Conjugate in Relapsed or Refractory Solid Tumors

Who this might be right for
Relapsed Solid NeoplasmRefractory CancerSolid Tumor, Adult
Sorrento Therapeutics, Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07368543
What this trial is testing

Sequencing SG vs. T-DXd in HER2-Low/TROP2-High Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Fudan University 216
Testing effectiveness (Phase 2)Looking for participantsNCT07193511
What this trial is testing

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

Who this might be right for
Solid Tumor CancerLocally AdvancedMetastatic Solid Tumors+1 more
Avenzo Therapeutics, Inc. 355
Large-scale testing (Phase 3)Looking for participantsNCT06103864
What this trial is testing

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 625
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07077564
What this trial is testing

The Efficacy of TROP2-ADC in Advanced Extrapulmonary High-Grade Neuroendocrine Neoplasms Failure of Standard Therapy

Who this might be right for
Neuroendocrine Neoplasms (Tumours)
Second Affiliated Hospital, School of Medicine, Zhejiang University 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07501169
What this trial is testing

Sacituzumab Tirumotecan in Combination With Anlotinib in Previously Treated Patients With Extensive-Stage Small Cell Lung Cancer (ES-SCLC)

Who this might be right for
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Sichuan University 33
Not applicableLooking for participantsNCT07151898
What this trial is testing

PET/CT for Trop2 ADC Response Evaluation NSCLC

Who this might be right for
NSCLCTrop2PET/CT
The First Affiliated Hospital of Xiamen University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06454890
What this trial is testing

Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-Small Cell Lung Cancer NSCLC
Henan Cancer Hospital 50
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