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Results for “Trop2”

94 trials

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Showing 20 of 94 results

Testing effectiveness (Phase 2)Looking for participantsNCT07589530
What this trial is testing

Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Solid TumorsTROP2-Expressing Solid Tumors
Beijing Biotech 60
Large-scale testing (Phase 3)Active Not RecruitingNCT05374512
What this trial is testing

Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Who this might be right for
Breast Cancer
AstraZeneca 644
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07077564
What this trial is testing

The Efficacy of TROP2-ADC in Advanced Extrapulmonary High-Grade Neuroendocrine Neoplasms Failure of Standard Therapy

Who this might be right for
Neuroendocrine Neoplasms (Tumours)
Second Affiliated Hospital, School of Medicine, Zhejiang University 35
Testing effectiveness (Phase 2)Ended earlyNCT06865677
What this trial is testing

Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas

Who this might be right for
Recurrent Platinum Resistant Epithelial Ovarian CarcinomaRecurrent Epithelial Endometrial CarcinomaRecurrent Epithelial Cervical Carcinoma
National Cancer Institute (NCI) 2
Testing effectiveness (Phase 2)Looking for participantsNCT05941507
What this trial is testing

Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 300
Large-scale testing (Phase 3)Looking for participantsNCT06851663
What this trial is testing

Trop2-targeted immunoPET Imaging of Solid Tumors

Who this might be right for
Solid TumorSolid CarcinomaUroepithelial Carcinoma+11 more
RenJi Hospital 400
Testing effectiveness (Phase 2)Looking for participantsNCT06878625
What this trial is testing

A Multicenter, Prospective, Cohort Study of Trop-2 ADC Combination Therapy for Advanced Triple-negative Breast Cancer

Who this might be right for
Evaluating the Efficacy of Trop-2 ADC Combination Therapy in Advanced Triple-Negative Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 138
Testing effectiveness (Phase 2)Looking for participantsNCT06715826
What this trial is testing

Target-specific immunoPET Imaging of Breast Cancer

Who this might be right for
Breast CancerBreast NeoplasmsBreast Cancer Metastatic
RenJi Hospital 200
Testing effectiveness (Phase 2)Looking for participantsNCT06793332
What this trial is testing

BrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC

Who this might be right for
Triple-Negative Breast Cancer (TNBC)Brain Metastases
Fudan University 39
Large-scale testing (Phase 3)Looking for participantsNCT06103864
What this trial is testing

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 625
Testing effectiveness (Phase 2)Looking for participantsNCT07471776
What this trial is testing

Study on Using TROP2-PET and 18F-FDG PET to Predict the Efficacy of Anti TROP2 ADC Treatment in Advanced Breast Cancer

Who this might be right for
Metastatic Breast Cancer ( HER2 Negative)
Fudan University 45
Not applicableNot Yet RecruitingNCT06934733
What this trial is testing

The Efficacy of Oral Cryotherapy in Preventing TROP2-ADC-Induced Oral Mucositis in Patients With Advanced Breast Cancer

Who this might be right for
Advanced or Metastatic Breast Cancer
Henan Cancer Hospital 124
Early research (Phase 1)Looking for participantsNCT07067567
What this trial is testing

AK146D1 for Injection in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Akeso 200
Early research (Phase 1)Not Yet RecruitingNCT07631013
What this trial is testing

Phase 1 Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cell In Patients With Oral Premalignant Lesions

Who this might be right for
Squamous Cell Carcinoma
M.D. Anderson Cancer Center 36
Not applicableLooking for participantsNCT07177482
What this trial is testing

ImmunoPET Targeting Trophoblast Cell-surface Antigen 2 (Trop-2) in Craniopharyngioma Patients

Who this might be right for
Craniopharyngioma
Deling Li 20
Testing effectiveness (Phase 2)Looking for participantsNCT07299747
What this trial is testing

Clinical Trial of VBC103 in Patients With Advanced Malignant Solid Tumors

Who this might be right for
Participants With Advanced Solid Tumor Malignancies
VelaVigo Bio Inc 255
Testing effectiveness (Phase 2)Looking for participantsNCT07179783
What this trial is testing

Sacituzumab Tirumotecan in Combination With Tagitanlimab in the Treatment of Aggressive Variant Prostate Cancer (AVPC) and Neuroendocrine Prostate Cancer (NEPC)

Who this might be right for
Prostate Cancer (Adenocarcinoma)Prostate Cancer Metastatic Castration-ResistantProstate Adenocarcinoma With Neuroendocrine Differentiation
Tianjin Medical University Second Hospital 28
Large-scale testing (Phase 3)Active Not RecruitingNCT05104866
What this trial is testing

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Who this might be right for
Breast Cancer
AstraZeneca 732
Early research (Phase 1)Looking for participantsNCT05969041
What this trial is testing

Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors

Who this might be right for
Epithelial Tumors, Malignant
Myeloid Therapeutics 48
Testing effectiveness (Phase 2)Looking for participantsNCT06851299
What this trial is testing

The Clinical Study of the Efficacy and Safety of Trop2-ADC Monotherapy or Combination Immunotherapy Strategy in the Treatment of Advanced Triple-negative Breast Cancer.

Who this might be right for
Metastatic Triple-negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 60
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