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Results for “Trypanosomiases, African”

31 trials

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Showing 20 of 31 results

Large-scale testing (Phase 3)Study completedNCT02184689
What this trial is testing

Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study

Who this might be right for
Human African Trypanosomiasis (HAT)
Drugs for Neglected Diseases 125
Not applicableStudy completedNCT06060600
What this trial is testing

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

Who this might be right for
Trypanosoma Brucei Rhodesiense; Infection
Paxmedica 345
Not applicableStudy completedNCT03356665
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection

Who this might be right for
African TrypanosomiasesWest African; TrypanosomiasisSleeping Sickness; West African+1 more
Institut de Recherche pour le Developpement 10,700
Not applicableStudy completedNCT05466630
What this trial is testing

Prospective Evaluation of the Specificity of Serological Tests for Human African Trypanosomiasis

Who this might be right for
Human African TrypanosomiasisSleeping SicknessTrypanosoma Brucei Gambiense; Infection+1 more
Institut de Recherche pour le Developpement 1,095
Large-scale testing (Phase 3)Ended earlyNCT00330148
What this trial is testing

Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Epicentre 435
Not applicableStudy completedNCT01766830
What this trial is testing

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)

Who this might be right for
Visceral LeishmaniasisHuman African TrypanosomiasisEnteric Fever+9 more
University Hospital, Geneva 1,927
Early research (Phase 1)Study completedNCT01533961
What this trial is testing

Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158

Who this might be right for
TrypanosomiasisTrypanosomiasis, AfricanProtozoan Infections+1 more
Drugs for Neglected Diseases 136
Early research (Phase 1)Study completedNCT05947604
What this trial is testing

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 20
Early research (Phase 1)Study completedNCT01340157
What this trial is testing

Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

Who this might be right for
PK in Healthy Volunteers
Drugs for Neglected Diseases 12
Not applicableWithdrawnNCT03394976
What this trial is testing

Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum Malaria

Who this might be right for
Human African Trypanosomiasis
Foundation for Innovative New Diagnostics, Switzerland
Early research (Phase 1)Study completedNCT02571062
What this trial is testing

Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market Formulation

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 30
Large-scale testing (Phase 3)Study completedNCT03974178
What this trial is testing

Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense

Who this might be right for
Trypanosomiasis, AfricanSleeping SicknessTrypanosoma Brucei Rhodesiense; Infection
Drugs for Neglected Diseases 45
Not applicableStudy completedNCT05637632
What this trial is testing

Assessment of Recombinant HAT-RDT Specificity

Who this might be right for
Human African Trypanosomiasis
Institute of Tropical Medicine, Belgium 1,504
Not applicableStudy completedNCT04099628
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP3 Post Elimination Monitoring

Who this might be right for
Human African TrypanosomiasisSleeping SicknessTrypanosoma Brucei Gambiense; Infection+3 more
Institut de Recherche pour le Developpement 13,747
Large-scale testing (Phase 3)Study completedNCT01685827
What this trial is testing

Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2

Who this might be right for
Human African Trypanosomiasis (HAT)Sleeping Sickness
Drugs for Neglected Diseases 394
Testing effectiveness (Phase 2)Study completedNCT00803933
What this trial is testing

Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

Who this might be right for
African Trypanosomiasis
Immtech Pharmaceuticals, Inc 111
Large-scale testing (Phase 3)Study completedNCT00146627
What this trial is testing

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 280
Post-approval studies (Phase 4)Study completedNCT00906880
What this trial is testing

Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic Phase

Who this might be right for
Human African Trypanosomiasis
Drugs for Neglected Diseases 630
Early research (Phase 1)Study completedNCT04270981
What this trial is testing

ADME Study of Acoziborole in Healthy Subjects

Who this might be right for
Trypanosomiases, African
Drugs for Neglected Diseases 6
Large-scale testing (Phase 3)Ended earlyNCT00489658
What this trial is testing

Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, Uganda

Who this might be right for
Trypanosomiasis, African
Epicentre 31
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