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Results for “Turcot Syndrome”

70 trials

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Showing 20 of 70 results

Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Looking for participantsNCT05093231
What this trial is testing

Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Cambridge University Hospitals NHS Foundation Trust 20
Not applicableNot Yet RecruitingNCT07625735
What this trial is testing

MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastric Cancer

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsLymph Node Metastasis+1 more
Shanghai Zhongshan Hospital 3,000
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Very early researchLooking for participantsNCT06305962
What this trial is testing

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Who this might be right for
PDL1 Gene MutationNon Small Cell Lung CancerSmall Cell Lung Cancer ( SCLC )+6 more
Radiopharm Theranostics, Ltd 30
Testing effectiveness (Phase 2)UnknownNCT03150706
What this trial is testing

Avelumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Asan Medical Center 33
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06646445
What this trial is testing

Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.

Who this might be right for
Colon Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 60
Early research (Phase 1)Study completedNCT03053466
What this trial is testing

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

Who this might be right for
Solid TumorMicrosatellite InstabilityMismatch Repair Deficiency+1 more
Apollomics (Australia) Pty. Ltd. 30
Testing effectiveness (Phase 2)Looking for participantsNCT06580574
What this trial is testing

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Who this might be right for
Gastric CancerColon CancerMSI-H+1 more
Peking University 34
Not applicableStudy completedNCT03460483
What this trial is testing

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

Who this might be right for
Endometrial AdenocarcinomaEndometrial CarcinomaLynch Syndrome+1 more
Ohio State University Comprehensive Cancer Center 1,001
Not applicableLooking for participantsNCT07829081
What this trial is testing

Research on Effective Strategies After Immunotherapy for Mismatch Repair-deficient Early-stage GI Tumors

Who this might be right for
Quality of Life (QOL)Mismatch Repair Deficient Colorectal CancerMicrosatellite Instability-High Colorectal Cancer+8 more
University Hospital, Basel, Switzerland 234
Early research (Phase 1)Ended earlyNCT05909995
What this trial is testing

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

Who this might be right for
MelanomaHepatocellular Carcinoma (HCC)Renal Cell Carcinoma (RCC)+3 more
Incyte Corporation 8
Early research (Phase 1)Study completedNCT03652077
What this trial is testing

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Who this might be right for
Cervical CancerGastric CancerStomach Cancer+18 more
Incyte Corporation 40
Testing effectiveness (Phase 2)Looking for participantsNCT07140679
What this trial is testing

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

Who this might be right for
Localized Colon CarcinomaStage IIB Colon Cancer AJCC v8Stage IIC Colon Cancer AJCC v8+1 more
Emory University 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07595523
What this trial is testing

Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair Deficiency

Who this might be right for
Gastric Cancer
Peking University Cancer Hospital & Institute 30
Not applicableUnknownNCT03757247
What this trial is testing

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation

Who this might be right for
Neurofibromatosis Type 1
Medical University Innsbruck 670
Testing effectiveness (Phase 2)Active Not RecruitingNCT03607890
What this trial is testing

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Who this might be right for
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 TherapyMSI-H Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Not applicableLooking for participantsNCT03452774
What this trial is testing

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Who this might be right for
Cancer, MetastaticCancerCancer of Pancreas+40 more
Massive Bio, Inc. 50,000
Testing effectiveness (Phase 2)Looking for participantsNCT05729646
What this trial is testing

Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Who this might be right for
Adenocarcinoma of the StomachAdenocarcinoma of Esophagogastric JunctionMismatch Repair Deficiency
Yu jiren 90
Early research (Phase 1)Study completedNCT03894618
What this trial is testing

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckMelanomaNon Small Cell Lung Cancer+10 more
Shattuck Labs, Inc. 49
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