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Results for “Type 1 Primary Hyperoxaluria”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Not applicableStudy completedNCT00589225
What this trial is testing

Primary Hyperoxaluria Mutation Genotyping

Who this might be right for
Primary Hyperoxaluria
Mayo Clinic 902
Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Not applicableNo Longer AvailableNCT05993416
What this trial is testing

Treatment of Primary Hyperoxaluria Type 1 With Nedosiran

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Not applicableWithdrawnNCT00875823
What this trial is testing

International Registry for Primary Hyperoxaluria

Who this might be right for
Primary HyperoxaluriaNephrocalcinosisKidney Stones
Mayo Clinic
Not applicableStudy completedNCT02830009
What this trial is testing

IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA

Who this might be right for
Primary Hyperoxaluria Type 1Idiopathic Hypercalciuria
Hospices Civils de Lyon 5
Very early researchActive Not RecruitingNCT06892301
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
Guangzhou Women and Children's Medical Center 2
Testing effectiveness (Phase 2)Study completedNCT05001269
What this trial is testing

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2+1 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 27
Testing effectiveness (Phase 2)Study completedNCT00283387
What this trial is testing

Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria
Mayo Clinic 15
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Looking for participantsNCT06839235
What this trial is testing

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Arbor Biotechnologies 23
Very early researchLooking for participantsNCT06511349
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
RenJi Hospital 21
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Large-scale testing (Phase 3)Active Not RecruitingNCT04042402
What this trial is testing

Long Term Extension Study in Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 75
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Early research (Phase 1)Study completedNCT04555486
What this trial is testing

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Who this might be right for
Primary Hyperoxaluria Type 3
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 6
Testing effectiveness (Phase 2)Study completedNCT03350451
What this trial is testing

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Who this might be right for
PH1Primary HyperoxaluriaRNAi Therapeutic+2 more
Alnylam Pharmaceuticals 20
Testing effectiveness (Phase 2)Study completedNCT01281878
What this trial is testing

Trial on Treatment of Patients With Primary Hyperoxaluria Type I With Pyridoxal-phosphate

Who this might be right for
Primary Hyperoxaluria Type I
University of Cologne 12
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