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Results for “Type 1 Primary Hyperoxaluria”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Study completedNCT03350451
What this trial is testing

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Who this might be right for
PH1Primary HyperoxaluriaRNAi Therapeutic+2 more
Alnylam Pharmaceuticals 20
Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Not applicableStudy completedNCT02340689
What this trial is testing

Primary Hyperoxaluria Mutation Genotyping/Phenotyping

Who this might be right for
Primary Hyperoxaluria
Mayo Clinic 1,235
Not applicableStudy completedNCT03067142
What this trial is testing

Proteomics of Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 93
Large-scale testing (Phase 3)Not Yet RecruitingNCT06465472
What this trial is testing

Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2Primary Hyperoxaluria Type 3
Biocodex 42
Early research (Phase 1)Study completedNCT04555486
What this trial is testing

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Who this might be right for
Primary Hyperoxaluria Type 3
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 6
Testing effectiveness (Phase 2)Study completedNCT05001269
What this trial is testing

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2+1 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 27
Not applicableStudy completedNCT02830009
What this trial is testing

IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA

Who this might be right for
Primary Hyperoxaluria Type 1Idiopathic Hypercalciuria
Hospices Civils de Lyon 5
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableApproved For MarketingNCT04125472
What this trial is testing

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria
Alnylam Pharmaceuticals
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Not applicableStudy completedNCT00589225
What this trial is testing

Primary Hyperoxaluria Mutation Genotyping

Who this might be right for
Primary Hyperoxaluria
Mayo Clinic 902
Not applicableLooking for participantsNCT02780297
What this trial is testing

Prospective Research Rare Kidney Stones (ProRKS)

Who this might be right for
HyperoxaluriaCystinuriaDent Disease+2 more
Mayo Clinic 220
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Not applicableWithdrawnNCT00875823
What this trial is testing

International Registry for Primary Hyperoxaluria

Who this might be right for
Primary HyperoxaluriaNephrocalcinosisKidney Stones
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT01281878
What this trial is testing

Trial on Treatment of Patients With Primary Hyperoxaluria Type I With Pyridoxal-phosphate

Who this might be right for
Primary Hyperoxaluria Type I
University of Cologne 12
Not applicableLooking for participantsNCT06225882
What this trial is testing

Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France.

Who this might be right for
Patients With PH1 Treated With Lumasiran in France
Hospices Civils de Lyon 100
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Testing effectiveness (Phase 2)Study completedNCT00283387
What this trial is testing

Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria
Mayo Clinic 15
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