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Results for “Undifferentiated Pleomorphic Sarcoma (UPS)”

8 trials

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Showing 8 of 8 results

Early research (Phase 1)Looking for participantsNCT06789172
What this trial is testing

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

Who this might be right for
Solid TumoursSarcomaHNSCC+9 more
Epkin 166
Testing effectiveness (Phase 2)Looking for participantsNCT07169344
What this trial is testing

Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma (Excluding GIST)Soft Tissue Sarcoma AdultSoft Tissue Sarcoma of the Trunk and Extremities+6 more
Oslo University Hospital 110
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Large-scale testing (Phase 3)WithdrawnNCT06370871
What this trial is testing

Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft Tissue SarcomaUndifferentiated Pleomorphic Sarcoma (UPS)Myxofibrosarcoma (MFS)
Boehringer Ingelheim
Testing effectiveness (Phase 2)Looking for participantsNCT07173972
What this trial is testing

Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.

Who this might be right for
Soft Tissue Sarcoma (STS)Soft Tissue Sarcoma AdultSoft Tissue Sarcoma of the Trunk and Extremities+7 more
Oslo University Hospital 40
Testing effectiveness (Phase 2)UnknownNCT04447274
What this trial is testing

Carilizumab in Combination With Apatinib in Subjects With Unresectable UPS and ASPS

Who this might be right for
Sarcoma
Chinese Academy of Medical Sciences 20
Testing effectiveness (Phase 2)Ended earlyNCT05017103
What this trial is testing

Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study

Who this might be right for
Locally Advanced Undifferentiated Pleomorphic SarcomaMetastatic Undifferentiated Pleomorphic SarcomaRecurrent Undifferentiated Pleomorphic Sarcoma+1 more
M.D. Anderson Cancer Center 6
Large-scale testing (Phase 3)Looking for participantsNCT06422806
What this trial is testing

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Who this might be right for
Metastatic Dedifferentiated LiposarcomaMetastatic Undifferentiated Pleomorphic SarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI) 365