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Results for “Unmethylated Glioblastoma”

52 trials

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Showing 20 of 52 results

Early research (Phase 1)Study completedNCT03452930
What this trial is testing

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma
M.D. Anderson Cancer Center 5
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Large-scale testing (Phase 3)Looking for participantsNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Testing effectiveness (Phase 2)Active Not RecruitingNCT05986851
What this trial is testing

Azeliragon in MGMT Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Cantex Pharmaceuticals 30
Early research (Phase 1)Active Not RecruitingNCT05236036
What this trial is testing

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Who this might be right for
AstrocytomaGlioblastomaGlioblastoma, IDH-Wildtype+2 more
Northwestern University 86
Early research (Phase 1)Ended earlyNCT03422094
What this trial is testing

Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Washington University School of Medicine 3
Testing effectiveness (Phase 2)Looking for participantsNCT05909618
What this trial is testing

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

Who this might be right for
Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma
Sheba Medical Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Early research (Phase 1)Ended earlyNCT03107780
What this trial is testing

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma+1 more
National Cancer Institute (NCI) 32
Testing effectiveness (Phase 2)Ended earlyNCT03866109
What this trial is testing

A Study Evaluating Temferon in Patients With Glioblastoma & Unmethylated MGMT

Who this might be right for
Glioblastoma Multiforme
Genenta Science 25
Early research (Phase 1)Looking for participantsNCT07343986
What this trial is testing

Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma

Who this might be right for
Glioblastoma (GBM)
University of Virginia 12
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Early research (Phase 1)Looking for participantsNCT06186401
What this trial is testing

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

Who this might be right for
EGFR Gene MutationGlioblastomaMGMT-Unmethylated Glioblastoma+1 more
Hideho Okada, MD, PhD 20
Testing effectiveness (Phase 2)UnknownNCT04224441
What this trial is testing

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Who this might be right for
Glioblastoma MultiformeMGMT-Unmethylated Glioblastoma
Marco G Paggi, MD, PhD 41
Testing effectiveness (Phase 2)Ended earlyNCT03927222
What this trial is testing

Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma

Who this might be right for
Glioblastoma
Mustafa Khasraw, MBChB, MD, FRCP, FRACP 6
Testing effectiveness (Phase 2)Study completedNCT03050736
What this trial is testing

Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 29
Testing effectiveness (Phase 2)UnknownNCT02928575
What this trial is testing

Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Bassam Abdulkarim 45
Early research (Phase 1)WithdrawnNCT04741984
What this trial is testing

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM

Who this might be right for
GlioblastomaGlioma, Malignant
Michael Gunn
Testing effectiveness (Phase 2)Looking for participantsNCT05871021
What this trial is testing

Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma

Who this might be right for
Glioblastoma
University Hospital Tuebingen 146
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07347210
What this trial is testing

Evaluation of UCPVax Vaccine +/- Pembrolizumab Combined With Standard Treatment as Adjuvant Therapy in Patients With Unmethylated MGMT Glioblastoma

Who this might be right for
Primary Glioblastoma
Centre Hospitalier Universitaire de Besancon 98
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