Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Unresectable (Stage III) Melanoma”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT06284590
What this trial is testing

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients

Who this might be right for
Melanoma Stage IIIMelanoma Stage IV
Philogen S.p.A. 162
Testing effectiveness (Phase 2)Ended earlyNCT02314143
What this trial is testing

Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib

Who this might be right for
Melanoma
GlaxoSmithKline 48
Early research (Phase 1)Study completedNCT03021460
What this trial is testing

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Metastatic MelanomaStage III Cutaneous Melanoma AJCC v7Stage IIIA Cutaneous Melanoma AJCC v7+4 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Ended earlyNCT01433991
What this trial is testing

E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Participants With Recurrent Glioblastoma or Unresectable Stage III or Stage IV Melanoma After Prior Systemic Therapy (Expansion Cohort and Phase 2)

Who this might be right for
Advanced Solid Tumors
Eisai Inc. 30
Large-scale testing (Phase 3)Study completedNCT03430297
What this trial is testing

A Randomized, Controlled, Multi-center, Phase III Clinical Study to Investigate Recombinant Humanized PD-1 Monoclonal Antibody Injection (JS001) Versus Dacarbazine as the 1st-line Therapy for Unresectable or Metastatic Melanoma

Who this might be right for
Metastatic MelanomaUnresectable Melanoma
Shanghai Junshi Bioscience Co., Ltd. 256
Testing effectiveness (Phase 2)Active Not RecruitingNCT06784648
What this trial is testing

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma MetastaticMelanoma of SkinMelanoma BRAF V600E/K Mutated+7 more
BioInvent International AB 35
Not applicableNo Longer AvailableNCT02142218
What this trial is testing

Expanded Access Program With Nivolumab to Treat Melanoma

Who this might be right for
Stage III (Unresectable) or Stage IV Advanced Melanoma
Bristol-Myers Squibb
Large-scale testing (Phase 3)Active Not RecruitingNCT04657991
What this trial is testing

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Pfizer 257
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Large-scale testing (Phase 3)Active Not RecruitingNCT02224781
What this trial is testing

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Melanoma+2 more
National Cancer Institute (NCI) 267
Not applicableNo Longer AvailableNCT02416232
What this trial is testing

Access Study of Trametinib for Subjects With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma

Who this might be right for
Melanoma
GlaxoSmithKline
Large-scale testing (Phase 3)Active Not RecruitingNCT05352672
What this trial is testing

Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Regeneron Pharmaceuticals 1,546
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT01989585
What this trial is testing

Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Malignant Solid Neoplasm+2 more
National Cancer Institute (NCI) 75
Testing effectiveness (Phase 2)Study completedNCT00591370
What this trial is testing

Phase II Trial of Extended-Dosing Temozolomide in Patients With Melanoma

Who this might be right for
Melanoma
Memorial Sloan Kettering Cancer Center 51
Testing effectiveness (Phase 2)Looking for participantsNCT04598009
What this trial is testing

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Who this might be right for
Melanoma Stage IIIMelanoma Stage IV
University of California, San Francisco 25
Large-scale testing (Phase 3)Active Not RecruitingNCT02339571
What this trial is testing

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Who this might be right for
Stage III Cutaneous Melanoma AJCC v7Stage IV Cutaneous Melanoma AJCC v6 and v7
National Cancer Institute (NCI) 600
Testing effectiveness (Phase 2)Looking for participantsNCT05655312
What this trial is testing

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

Who this might be right for
Recurrent Melanoma (Skin)Metastatic MelanomaMelanoma Stage IV+1 more
Perspective Therapeutics 300
Testing effectiveness (Phase 2)WithdrawnNCT02452281
What this trial is testing

Pilot Study to Evaluate the Effects of a Vaccine (HSPPC-96) Combined With Ipilimumab in Patients With Advanced Melanoma

Who this might be right for
Melanoma
Rabih Said
Large-scale testing (Phase 3)Study completedNCT02599402
What this trial is testing

Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma

Who this might be right for
Melanoma
Bristol-Myers Squibb 533
Next Page