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Results for “Unresectable Adenocarcinoma of the Esophagus”

40 trials

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Showing 20 of 40 results

Early research (Phase 1)Study completedNCT00537121
What this trial is testing

Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer

Who this might be right for
Esophageal CancerGastric CancerLiver Cancer
Roswell Park Cancer Institute 23
Large-scale testing (Phase 3)Looking for participantsNCT06203600
What this trial is testing

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastric AdenocarcinomaAdvanced Gastroesophageal Junction Adenocarcinoma+13 more
National Cancer Institute (NCI) 224
Very early researchStudy completedNCT03395847
What this trial is testing

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+22 more
M.D. Anderson Cancer Center 9
Testing effectiveness (Phase 2)Study completedNCT00107341
What this trial is testing

Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Unresectable, Metastatic Cancer of the Esophagus or Gastroesophageal Junction

Who this might be right for
Esophageal Cancer
Alliance for Clinical Trials in Oncology 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT05945823
What this trial is testing

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal CancerEsophageal AdenocarcinomaEsophageal Squamous Cell Cancer+2 more
Taiho Oncology, Inc. 53
Testing effectiveness (Phase 2)Study completedNCT03777813
What this trial is testing

Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer

Who this might be right for
Esophagus CancerUnresectable Malignant Neoplasm
UNICANCER 112
Large-scale testing (Phase 3)Study completedNCT04499924
What this trial is testing

Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaEsophageal Adenocarcinoma
Seagen Inc. 17
Testing effectiveness (Phase 2)Study completedNCT00032123
What this trial is testing

Erlotinib in Treating Patients With Locally Advanced or Metastatic Stomach Cancer or Gastroesophageal Junction Cancer

Who this might be right for
Esophageal CancerGastric Cancer
SWOG Cancer Research Network
Early research (Phase 1)Active Not RecruitingNCT04460937
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Who this might be right for
Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+56 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT00109850
What this trial is testing

S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Cancer
SWOG Cancer Research Network 22
Early research (Phase 1)Study completedNCT00252889
What this trial is testing

Doxil Topotecan Doublet Cancer Study

Who this might be right for
Small Cell Lung CancerPancreatic CancerHead and Neck Cancer+2 more
Christiana Care Health Services 20
Testing effectiveness (Phase 2)Looking for participantsNCT06628310
What this trial is testing

Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Who this might be right for
Locally Advanced Unresectable or Metastatic Gastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaEsophageal Adenocarcinoma
AbbVie 180
Large-scale testing (Phase 3)Active Not RecruitingNCT05568095
What this trial is testing

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Who this might be right for
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Arcus Biosciences, Inc. 1,040
Not applicableStudy completedNCT00900094
What this trial is testing

UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer

Who this might be right for
Breast CancerColorectal CancerEsophageal Cancer+4 more
University of Michigan Rogel Cancer Center 200
Testing effectiveness (Phase 2)Study completedNCT00215462
What this trial is testing

Vinorelbine in Unresectable or Metastatic Esophageal and Gastric Adenocarcinoma

Who this might be right for
Esophageal CancerGastric CancerStomach Cancer
Dana-Farber Cancer Institute 32
Large-scale testing (Phase 3)Active Not RecruitingNCT05152147
What this trial is testing

Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Who this might be right for
Gastric NeoplasmsGastroesophageal AdenocarcinomaEsophageal Adenocarcinoma
Jazz Pharmaceuticals 920
Not applicableUnknownNCT04825470
What this trial is testing

Liver Transplantation for Unresectable GIST Liver Metastases

Who this might be right for
Liver DiseasesLiver CancerLiver Metastases+25 more
Hospital Universitario Virgen de la Arrixaca 50
Early research (Phase 1)Study completedNCT00101972
What this trial is testing

RAV12 in Treating Patients With Metastatic or Recurrent Adenocarcinoma

Who this might be right for
Cancer
MacroGenics 53
Testing effectiveness (Phase 2)Study completedNCT01178944
What this trial is testing

Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Undifferentiated CarcinomaGastric Adenocarcinoma+14 more
Roswell Park Cancer Institute 35
Testing effectiveness (Phase 2)Ended earlyNCT04683939
What this trial is testing

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors

Who this might be right for
Solid TumorGastric CancerGastroesophageal Junction Adenocarcinoma+5 more
BioNTech SE 13
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