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Results for “Unresectable Adenocarcinoma of the Esophagus”

42 trials

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Showing 20 of 42 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05568095
What this trial is testing

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Who this might be right for
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Arcus Biosciences, Inc. 1,040
Not applicableUnknownNCT04825470
What this trial is testing

Liver Transplantation for Unresectable GIST Liver Metastases

Who this might be right for
Liver DiseasesLiver CancerLiver Metastases+25 more
Hospital Universitario Virgen de la Arrixaca 50
Early research (Phase 1)Study completedNCT00101972
What this trial is testing

RAV12 in Treating Patients With Metastatic or Recurrent Adenocarcinoma

Who this might be right for
Cancer
MacroGenics 53
Testing effectiveness (Phase 2)Looking for participantsNCT05651594
What this trial is testing

Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+8 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Study completedNCT00591123
What this trial is testing

Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia

Who this might be right for
Unresectable Adenocarcinoma of the EsophagusMetastatic Adenocarcinoma of the EsophagusUnresectable Adenocarcinoma of Gastric Cardia+1 more
Translational Oncology Research International 38
Testing effectiveness (Phase 2)Study completedNCT00215462
What this trial is testing

Vinorelbine in Unresectable or Metastatic Esophageal and Gastric Adenocarcinoma

Who this might be right for
Esophageal CancerGastric CancerStomach Cancer
Dana-Farber Cancer Institute 32
Testing effectiveness (Phase 2)Looking for participantsNCT06628310
What this trial is testing

Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Who this might be right for
Locally Advanced Unresectable or Metastatic Gastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaEsophageal Adenocarcinoma
AbbVie 180
Not applicableStudy completedNCT01295086
What this trial is testing

Taxotere®, Eloxatin® and Xeloda® (TEX) in Combination With Herceptin® as Treatment for HER2 Positive Non-resectable Cancer

Who this might be right for
Adenocarcinoma
Odense University Hospital 27
Large-scale testing (Phase 3)Study completedNCT04499924
What this trial is testing

Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaEsophageal Adenocarcinoma
Seagen Inc. 17
Early research (Phase 1)Study completedNCT00252889
What this trial is testing

Doxil Topotecan Doublet Cancer Study

Who this might be right for
Small Cell Lung CancerPancreatic CancerHead and Neck Cancer+2 more
Christiana Care Health Services 20
Testing effectiveness (Phase 2)Ended earlyNCT00012246
What this trial is testing

Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract

Who this might be right for
Colorectal CancerEsophageal CancerExtrahepatic Bile Duct Cancer+4 more
The University of Texas Medical Branch, Galveston 7
Testing effectiveness (Phase 2)Study completedNCT03777813
What this trial is testing

Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer

Who this might be right for
Esophagus CancerUnresectable Malignant Neoplasm
UNICANCER 112
Not applicableStudy completedNCT00900094
What this trial is testing

UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer

Who this might be right for
Breast CancerColorectal CancerEsophageal Cancer+4 more
University of Michigan Rogel Cancer Center 200
Testing effectiveness (Phase 2)Study completedNCT00096083
What this trial is testing

Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Cancer
Delcath Systems Inc. 56
Early research (Phase 1)Study completedNCT06056024
What this trial is testing

Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus

Who this might be right for
Solid Tumor, KRAS Mutation
Boehringer Ingelheim 47
Large-scale testing (Phase 3)Looking for participantsNCT05677490
What this trial is testing

MFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastric AdenocarcinomaAdvanced Gastroesophageal Junction Adenocarcinoma+12 more
Alliance for Clinical Trials in Oncology 382
Very early researchStudy completedNCT03395847
What this trial is testing

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+22 more
M.D. Anderson Cancer Center 9
Testing effectiveness (Phase 2)Study completedNCT01178944
What this trial is testing

Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Undifferentiated CarcinomaGastric Adenocarcinoma+14 more
Roswell Park Cancer Institute 35
Early research (Phase 1)Not Yet RecruitingNCT07594548
What this trial is testing

Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+13 more
Northwestern University 18
Early research (Phase 1)WithdrawnNCT02205463
What this trial is testing

KD019 and Trastuzumab in Patients With Esophagus, Gastroesophageal Junction and Stomach Cancer

Who this might be right for
Esophageal CancerStomach Cancer
NYU Langone Health
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