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Results for “Unresectable Esophageal Carcinoma”

201 trials

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Showing 20 of 201 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Study completedNCT00215995
What this trial is testing

Cisplatin and Irinotecan Chemotherapy, Followed by ZD 1839 (Iressa) in Patients With Esophageal or Gastric Carcinomas

Who this might be right for
Esophageal CancerGastric Cancer
H. Lee Moffitt Cancer Center and Research Institute 21
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Early research (Phase 1)Study completedNCT01437007
What this trial is testing

TKM 080301 for Primary or Secondary Liver Cancer

Who this might be right for
Colorectal Cancer With Hepatic MetastasesPancreas Cancer With Hepatic MetastaseGastric Cancer With Hepatic Metastase+2 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Active Not RecruitingNCT05539430
What this trial is testing

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Who this might be right for
Gastric CancerGastroesophageal-junction CancerEsophageal Cancer+1 more
Legend Biotech USA Inc 56
Not applicableEnrolling By InvitationNCT06715501
What this trial is testing

Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Esophageal Squamous Cell CarcinomaII-IIIB Stages
First Affiliated Hospital of Ningbo University 20
Large-scale testing (Phase 3)Active Not RecruitingNCT04704934
What this trial is testing

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Who this might be right for
Gastric Cancer, AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Daiichi Sankyo 490
Testing effectiveness (Phase 2)Looking for participantsNCT06709417
What this trial is testing

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Shanghai Chest Hospital 52
Testing effectiveness (Phase 2)UnknownNCT03011255
What this trial is testing

Combination of Radiation Therapy and Peptide Specific CTL Therapy in Treating Patients With Esophageal Cancer

Who this might be right for
Esophageal NeoplasmsEsophageal DiseasesDigestive System Diseases
Shixiu Wu 20
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Testing effectiveness (Phase 2)Study completedNCT00096083
What this trial is testing

Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Cancer
Delcath Systems Inc. 56
Testing effectiveness (Phase 2)UnknownNCT02636088
What this trial is testing

Definitive Chemoradiotherapy and Cetuximab in the Treatment of Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Neoplasm
Gabriella Alexandersson von Döbeln 51
Early research (Phase 1)Study completedNCT00049296
What this trial is testing

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Case Comprehensive Cancer Center 26
Early research (Phase 1)Study completedNCT04316689
What this trial is testing

First-in-human Study of S-588210 (S-488210+S-488211)

Who this might be right for
Lung CancerHead and Neck CancerBladder Cancer+2 more
Shionogi 10
Testing effectiveness (Phase 2)UnknownNCT04054518
What this trial is testing

Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Tiago Biachi 22
Large-scale testing (Phase 3)Study completedNCT00680901
What this trial is testing

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Who this might be right for
Neoplasms, Gastrointestinal Tract
Novartis Pharmaceuticals 545
Testing effectiveness (Phase 2)Looking for participantsNCT07086469
What this trial is testing

Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
ToripalimabSurufatinibNeoadjuvant Immunochemotherapy+2 more
Sun Yat-sen University 69
Early research (Phase 1)Active Not RecruitingNCT04491942
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical Carcinoma+31 more
National Cancer Institute (NCI) 74
Early research (Phase 1)Looking for participantsNCT05983432
What this trial is testing

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

Who this might be right for
Non Small Cell Lung CancerEsophageal CancerSmall Cell Lung Cancer+7 more
SystImmune Inc. 540
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