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Results for “Unresectable Head and Neck Squamous Cell Carcinoma”

176 trials

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Showing 20 of 176 results

Testing effectiveness (Phase 2)Study completedNCT00101348
What this trial is testing

Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell CarcinomaRecurrent Adenoid Cystic Carcinoma of the Oral CavityRecurrent Basal Cell Carcinoma of the Lip+64 more
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Looking for participantsNCT06709417
What this trial is testing

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Shanghai Chest Hospital 52
Early research (Phase 1)Active Not RecruitingNCT02495896
What this trial is testing

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic AdenocarcinomaNon-Resectable Cholangiocarcinoma+13 more
University of Southern California 61
Testing effectiveness (Phase 2)WithdrawnNCT04834349
What this trial is testing

Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer

Who this might be right for
Recurrent Head and Neck Squamous Cell CarcinomaUnresectable Head and Neck Squamous Cell Carcinoma
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Testing effectiveness (Phase 2)Active Not RecruitingNCT04844385
What this trial is testing

Toripalimab Plus Neoadjuvant Chemotherapy Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Sun Yat-sen University 124
Early research (Phase 1)Looking for participantsNCT06778863
What this trial is testing

CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorMetastatic Solid Tumor+8 more
Clasp Therapeutics, Inc. 90
Large-scale testing (Phase 3)Study completedNCT04540211
What this trial is testing

Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma

Who this might be right for
Esophageal Cancer
Hoffmann-La Roche 461
Early research (Phase 1)Study completedNCT04672434
What this trial is testing

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 48
Testing effectiveness (Phase 2)Study completedNCT03624231
What this trial is testing

Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Ulrich Keilholz 18
Testing effectiveness (Phase 2)Ended earlyNCT02345330
What this trial is testing

Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)

Who this might be right for
Head and Neck Squamous Cell Carcinoma
OncoSec Medical Incorporated 4
Testing effectiveness (Phase 2)Study completedNCT02058849
What this trial is testing

Randomized Study of Beet Root in Locally Advanced Squamous Cell Cancer of the Head and Neck

Who this might be right for
Mucositis
David Travis Thomas 13
Early research (Phase 1)Study completedNCT03229278
What this trial is testing

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmMetastatic Melanoma+26 more
Rutgers, The State University of New Jersey 14
Testing effectiveness (Phase 2)UnknownNCT04514835
What this trial is testing

A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 44
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Early research (Phase 1)Looking for participantsNCT05107674
What this trial is testing

NX-1607 in Adults With Advanced Malignancies

Who this might be right for
Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more
Nurix Therapeutics, Inc. 345
Testing effectiveness (Phase 2)Looking for participantsNCT06016920
What this trial is testing

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHNSCC
Nykode Therapeutics ASA 51
Testing effectiveness (Phase 2)Study completedNCT03625323
What this trial is testing

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

Who this might be right for
NSCLCHNSCC
Immutep S.A.S. 187
Large-scale testing (Phase 3)Active Not RecruitingNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 351
Testing effectiveness (Phase 2)Looking for participantsNCT06988956
What this trial is testing

Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital with Nanjing Medical University 95
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