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Results for “Unresectable Locally Advanced Cancer”

1,062 trials

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Showing 20 of 1,062 results

Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Testing effectiveness (Phase 2)Study completedNCT03112590
What this trial is testing

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Who this might be right for
Breast CancerBreast Cancer, MaleBreast Cancer Female+1 more
H. Lee Moffitt Cancer Center and Research Institute 51
Testing effectiveness (Phase 2)Study completedNCT03108131
What this trial is testing

Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors

Who this might be right for
Skin Squamous Cell CarcinomaAppendix AdenocarcinomaRare Lesion+9 more
M.D. Anderson Cancer Center 49
Early research (Phase 1)Study completedNCT04106856
What this trial is testing

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer

Who this might be right for
Borderline Resectable Pancreatic AdenocarcinomaLocally Advanced Pancreatic Ductal AdenocarcinomaLocally Advanced Unresectable Pancreatic Adenocarcinoma+4 more
University of Utah 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT06700421
What this trial is testing

Phase II Clinical Study of Adebrelimab Combined with Apatinib in the Treatment of Locally Advanced Non-small Cell Lung Cancer Patients with Radiation Pneumonitis

Who this might be right for
Unresectable Locally Advanced Non-small Cell Lung Cancer
Wei Zhou 32
Large-scale testing (Phase 3)Study completedNCT03984214
What this trial is testing

Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancer

Who this might be right for
Pancreatic Cancer Non-resectableChemotherapy-induced Nausea and VomitingPancreatic Cancer Metastatic
Arbeitsgemeinschaft medikamentoese Tumortherapie 109
Large-scale testing (Phase 3)Study completedNCT00471146
What this trial is testing

Study Of Gemcitabine Plus AG-013736 Versus Gemcitabine For Advanced Pancreatic Cancer.

Who this might be right for
Carcinoma, Pancreatic Ductal
Pfizer 630
Not applicableStudy completedNCT05902494
What this trial is testing

HER2 and LA/mUC: A Multi-country Chart Review Cohort Study

Who this might be right for
Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer 389
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06586294
What this trial is testing

Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 294
Large-scale testing (Phase 3)Active Not RecruitingNCT06382142
What this trial is testing

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer(PANKU-Breast02)

Who this might be right for
Triple-Negative Breast Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 418
Testing effectiveness (Phase 2)Looking for participantsNCT07742332
What this trial is testing

Targeted Induction Therapy for Stage III Unresectable EGFR Mutant Positive NSCLC

Who this might be right for
EGFRNSCLC (Non-small Cell Lung Cancer)Locally Advanced Non-Small Cell Lung Cancer+2 more
Peng Zhang 160
Not applicableStudy completedNCT01945762
What this trial is testing

Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer

Who this might be right for
Symptomatic, Aggressive, Sporadic, Unresectable, LocallyAdvanced/Metastatic Medullary Thyroid Cancer (MTC)
Genzyme, a Sanofi Company 31
Early research (Phase 1)Study completedNCT03801902
What this trial is testing

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

Who this might be right for
Locally Advanced Lung Non-Small Cell CarcinomaLocally Recurrent Lung Non-Small Cell CarcinomaStage II Lung Cancer AJCC v8+2 more
National Cancer Institute (NCI) 26
Not applicableStudy completedNCT05078775
What this trial is testing

Medical Food for the Dietary Management of Advanced/Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic AdenocarcinomaLocally Advanced Unresectable Pancreatic Adenocarcinoma
Faeth Therapeutics 39
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Testing effectiveness (Phase 2)Study completedNCT02767557
What this trial is testing

Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab in Pancreatic Cancer Patients

Who this might be right for
Unresectable Pancreatic Carcinoma
Herlev Hospital 147
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Early research (Phase 1)Active Not RecruitingNCT05539430
What this trial is testing

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Who this might be right for
Gastric CancerGastroesophageal-junction CancerEsophageal Cancer+1 more
Legend Biotech USA Inc 56
Not applicableEnrolling By InvitationNCT06715501
What this trial is testing

Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Esophageal Squamous Cell CarcinomaII-IIIB Stages
First Affiliated Hospital of Ningbo University 20
Testing effectiveness (Phase 2)Looking for participantsNCT06827236
What this trial is testing

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

Who this might be right for
Locally Advanced Breast CancerUnresectable Breast CarcinomaMetastatic Breast Cancer
BioNTech SE 380
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