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Results for “Unresectable Locally Advanced or Metastatic Cancer”

611 trials

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Showing 20 of 611 results

Large-scale testing (Phase 3)Ended earlyNCT04335006
What this trial is testing

Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 80
Testing effectiveness (Phase 2)Study completedNCT00301899
What this trial is testing

Trastuzumab and Pertuzumab in Treating Patients With Unresectable Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Trastuzumab

Who this might be right for
Breast Cancer
National Institutes of Health Clinical Center (CC) 37
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Early research (Phase 1)Study completedNCT04094506
What this trial is testing

Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Astellas Pharma Inc 9
Early research (Phase 1)Looking for participantsNCT06349408
What this trial is testing

IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd. 250
Early research (Phase 1)Study completedNCT05954871
What this trial is testing

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerNon-Small Cell Lung Cancer
Genentech, Inc. 10
Large-scale testing (Phase 3)Active Not RecruitingNCT05043090
What this trial is testing

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

Who this might be right for
Papillary Renal Cell Carcinoma
AstraZeneca 148
Not applicableStudy completedNCT00253708
What this trial is testing

Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Cancer
Beth Israel Deaconess Medical Center 39
Testing effectiveness (Phase 2)Study completedNCT03543813
What this trial is testing

PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL

Who this might be right for
Solid Tumor, AdultHead and Neck CancerNon Small Cell Lung Cancer+2 more
CytomX Therapeutics 133
Post-approval studies (Phase 4)Study completedNCT01496313
What this trial is testing

To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer

Who this might be right for
Thyroid Cancer
Sanofi 81
Large-scale testing (Phase 3)Study completedNCT02049905
What this trial is testing

Phase 3 Study to Treat Patients With Soft Tissue Sarcomas

Who this might be right for
Metastatic, Locally Advanced or Unresectable Soft Tissue Sarcoma
ImmunityBio, Inc. 433
Early research (Phase 1)Study completedNCT03589651
What this trial is testing

INCMGA00012 in Combination With Other Therapies in Patients With Advanced Solid Tumors

Who this might be right for
Unresectable or Metastatic Solid Tumors
Incyte Corporation 83
Not applicableUnknownNCT05349045
What this trial is testing

Angiogenesis Inhibitor Plus Anti-PD-1/PD-L1 Antibody in Advanced Esophageal Cancer

Who this might be right for
Esophageal Neoplasms
The First Affiliated Hospital of Zhengzhou University 300
Testing effectiveness (Phase 2)UnknownNCT02268747
What this trial is testing

Efficacy and Safety of Dacomitinib in the Treatment of Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 43
Testing effectiveness (Phase 2)Looking for participantsNCT05988814
What this trial is testing

Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy

Who this might be right for
Metastatic Pancreatic Cancer
Centre Georges Francois Leclerc 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05897138
What this trial is testing

Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Who this might be right for
Hepatocellular Carcinoma
Fujian Cancer Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06413745
What this trial is testing

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

Who this might be right for
HER2 Expression / Amplification in Patients With Biliary Tract Cancer
Jiangsu HengRui Medicine Co., Ltd. 65
Testing effectiveness (Phase 2)Ended earlyNCT05220098
What this trial is testing

First-in-Human Study of TAK-280 in Participants With Solid Tumors

Who this might be right for
Unresectable Locally Advanced or Metastatic Cancer
Takeda 69
Large-scale testing (Phase 3)Looking for participantsNCT07043400
What this trial is testing

Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Metastatic Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
BeOne Medicines 351
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