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Results for “Unresectable Locally Advanced or Metastatic Melanoma”

39 trials

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Showing 20 of 39 results

Not applicableStudy completedNCT00253708
What this trial is testing

Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Cancer
Beth Israel Deaconess Medical Center 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT05620134
What this trial is testing

Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
CancerTumor, SolidAdvanced Solid Tumor+19 more
Salubris Biotherapeutics Inc 263
Large-scale testing (Phase 3)Study completedNCT00110019
What this trial is testing

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Mucosal MelanomaRecurrent MelanomaStage IIIA Skin Melanoma+3 more
National Cancer Institute (NCI) 823
Testing effectiveness (Phase 2)Looking for participantsNCT06413680
What this trial is testing

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

Who this might be right for
MelanomaClear-Cell Renal-Cell Carcinoma (ccRCC)Advanced Solid Tumors
Regeneron Pharmaceuticals 240
Testing effectiveness (Phase 2)Ended earlyNCT04768881
What this trial is testing

Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma

Who this might be right for
Locally Advanced Unresectable or Metastatic Melanoma
Karyopharm Therapeutics Inc 15
Testing effectiveness (Phase 2)Study completedNCT02583516
What this trial is testing

Clinical Trial to Evaluate the Efficacy of Vemurafenib in Combination With Cobimetinib (Continuous and Intermittent) in BRAFV600-mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Grupo Español Multidisciplinar de Melanoma 70
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Early research (Phase 1)Active Not RecruitingNCT05973487
What this trial is testing

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more
TScan Therapeutics, Inc. 840
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT01474551
What this trial is testing

Vemurafenib (R05185426) in Poor Performance Status Patients With Unresectable Locally Advanced or Metastatic Melanoma Harboring a V600E/K Mutation

Who this might be right for
Melanoma
Memorial Sloan Kettering Cancer Center 2
Not applicableActive Not RecruitingNCT05812027
What this trial is testing

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon Small Cell Lung Cancer+4 more
TScan Therapeutics, Inc. 1,150
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Large-scale testing (Phase 3)Study completedNCT02908672
What this trial is testing

Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma

Who this might be right for
Melanoma
Hoffmann-La Roche 514
Testing effectiveness (Phase 2)Ended earlyNCT01586195
What this trial is testing

Study Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600E

Who this might be right for
Malignant Melanoma
Genentech, Inc. 31
Testing effectiveness (Phase 2)Looking for participantsNCT07280832
What this trial is testing

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma

Who this might be right for
Unresectable Locally Advanced or Metastatic Melanoma
Shanghai JMT-Bio Inc. 188
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Looking for participantsNCT06797297
What this trial is testing

Evaluate the Efficacy and Safety of IBI363 Monotherapy Compared to Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal or Acral Melanoma Who Had Not Previously Received Systemic Therapy

Who this might be right for
Melanoma
Innovent Biologics (Suzhou) Co. Ltd. 180
Early research (Phase 1)Looking for participantsNCT05098210
What this trial is testing

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more
Fred Hutchinson Cancer Center 25
Large-scale testing (Phase 3)Active Not RecruitingNCT04657991
What this trial is testing

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Pfizer 257
Testing effectiveness (Phase 2)Study completedNCT01320085
What this trial is testing

A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma

Who this might be right for
BRAF or NRAS Mutant Metastatic Melanoma
Pfizer 183
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