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Results for “Unresectable Malignant Solid Neoplasm”

131 trials

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Showing 20 of 131 results

Early research (Phase 1)Ended earlyNCT04168320
What this trial is testing

SBRT-based PArtial Tumor Irradiation of HYpoxic Segment

Who this might be right for
Bystander EffectAbscopal EffectUnresectable Malignant Solid Neoplasm+1 more
Klinikum Klagenfurt am Wörthersee 30
Early research (Phase 1)Looking for participantsNCT06911008
What this trial is testing

MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
Mayo Clinic 42
Early research (Phase 1)Active Not RecruitingNCT02595931
What this trial is testing

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Lung Small Cell CarcinomaMetastatic Malignant Solid Neoplasm+15 more
National Cancer Institute (NCI) 66
Early research (Phase 1)Study completedNCT01169584
What this trial is testing

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients

Who this might be right for
NeuroblastomaRhabdomyosarcomaLymphoma+2 more
Jennerex Biotherapeutics 6
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Early research (Phase 1)Active Not RecruitingNCT01787500
What this trial is testing

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Who this might be right for
BRAF NP_004324.2:p.V600XKRAS wt AlleleMetastatic Malignant Solid Neoplasm+4 more
M.D. Anderson Cancer Center 33
Early research (Phase 1)Study completedNCT02503709
What this trial is testing

Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Solid Neoplasm
National Cancer Institute (NCI) 29
Early research (Phase 1)Looking for participantsNCT05372640
What this trial is testing

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+3 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Ended earlyNCT02419495
What this trial is testing

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+26 more
M.D. Anderson Cancer Center 221
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT02498613
What this trial is testing

Cediranib in Combination With Olaparib in Advanced Solid Tumors

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Lung Non-Small Cell CarcinomaMetastatic Lung Small Cell Carcinoma+23 more
National Cancer Institute (NCI) 122
Testing effectiveness (Phase 2)Active Not RecruitingNCT02079740
What this trial is testing

Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 96
Testing effectiveness (Phase 2)Looking for participantsNCT06209580
What this trial is testing

AMT-253 in Patients With Advanced Solid Tumours

Who this might be right for
Malignant MelanomaAdvanced Solid Tumors
Multitude Therapeutics Inc. 96
Early research (Phase 1)Study completedNCT03229278
What this trial is testing

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmMetastatic Melanoma+26 more
Rutgers, The State University of New Jersey 14
Testing effectiveness (Phase 2)Looking for participantsNCT07105215
What this trial is testing

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 312
Early research (Phase 1)Looking for participantsNCT05803382
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Malignant Solid NeoplasmStage IV Colorectal Cancer AJCC v8+2 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT06016062
What this trial is testing

RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Solid Tumor
RemeGen Co., Ltd. 221
Testing effectiveness (Phase 2)Active Not RecruitingNCT01989585
What this trial is testing

Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Malignant Solid Neoplasm+2 more
National Cancer Institute (NCI) 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT04957615
What this trial is testing

Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expression

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Solid Neoplasm
M.D. Anderson Cancer Center 16
Early research (Phase 1)Study completedNCT02317874
What this trial is testing

Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 43
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