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Results for “Unresectable Malignant Solid Neoplasm”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT07137416
What this trial is testing

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast Carcinoma+13 more
National Cancer Institute (NCI) 36
Early research (Phase 1)Study completedNCT03218826
What this trial is testing

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Breast CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Prostate Carcinoma+23 more
National Cancer Institute (NCI) 23
Early research (Phase 1)Study completedNCT02159989
What this trial is testing

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmFibrolamellar CarcinomaMetastatic Malignant Solid Neoplasm+5 more
National Cancer Institute (NCI) 83
Not applicableUnknownNCT00072488
What this trial is testing

Whole-Body MRI and Conventional Imaging in Detecting Distant Metastases in Young Patients With Solid Tumors or Lymphoma

Who this might be right for
LymphomaNeuroblastomaSarcoma
American College of Radiology Imaging Network 226
Testing effectiveness (Phase 2)Active Not RecruitingNCT03872427
What this trial is testing

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmNF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor+1 more
National Cancer Institute (NCI) 54
Early research (Phase 1)Looking for participantsNCT05111561
What this trial is testing

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRefractory Malignant Solid Neoplasm+2 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT02079740
What this trial is testing

Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 96
Early research (Phase 1)Looking for participantsNCT06911008
What this trial is testing

MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
Mayo Clinic 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT02721732
What this trial is testing

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Who this might be right for
Advanced Malignant Solid NeoplasmCarcinoma of Unknown PrimaryMetastatic Adrenal Gland Pheochromocytoma+16 more
M.D. Anderson Cancer Center 157
Early research (Phase 1)Active Not RecruitingNCT04294628
What this trial is testing

Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRefractory Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI) 62
Early research (Phase 1)Study completedNCT02536469
What this trial is testing

HuMax-IL8 (Interleukin8) in Patients With Advanced Malignant Solid Tumors

Who this might be right for
Solid Tumor
Bristol-Myers Squibb 15
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Early research (Phase 1)Active Not RecruitingNCT04491942
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical Carcinoma+31 more
National Cancer Institute (NCI) 74
Early research (Phase 1)Active Not RecruitingNCT01364051
What this trial is testing

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Who this might be right for
Metastatic MelanomaRefractory Malignant Solid NeoplasmStage IV Cutaneous Melanoma AJCC v6 and v7+1 more
National Cancer Institute (NCI) 19
Testing effectiveness (Phase 2)Looking for participantsNCT05327010
What this trial is testing

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 88
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Early research (Phase 1)Study completedNCT01787500
What this trial is testing

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Who this might be right for
BRAF NP_004324.2:p.V600XKRAS wt AlleleMetastatic Malignant Solid Neoplasm+4 more
M.D. Anderson Cancer Center 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06873854
What this trial is testing

LM-108 in Combination With Toripalimab in Subjects With Advanced Solid Tumours

Who this might be right for
Advanced Solid Tumor
LaNova Medicines Limited 84
Testing effectiveness (Phase 2)WithdrawnNCT03326258
What this trial is testing

Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmEstrogen Receptor NegativeGPNMB Positive+15 more
National Cancer Institute (NCI)
Early research (Phase 1)Ended earlyNCT02706392
What this trial is testing

Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid NeoplasmMetastatic Lung Non-Small Cell Carcinoma+10 more
Fred Hutchinson Cancer Center 21
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