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Results for “Unresectable Melanoma”

453 trials

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Showing 20 of 453 results

Large-scale testing (Phase 3)Study completedNCT01515189
What this trial is testing

Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab

Who this might be right for
Melanoma
Bristol-Myers Squibb 831
Testing effectiveness (Phase 2)Active Not RecruitingNCT05089370
What this trial is testing

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

Who this might be right for
Malignant Melanoma
University of Colorado, Denver 8
Testing effectiveness (Phase 2)Study completedNCT03278665
What this trial is testing

4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy

Who this might be right for
Malignant Melanoma
4SC AG 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT03122522
What this trial is testing

Evaluate Adaptive Dosing of Ipilimumab and Nivolumab Combination Immunotherapy

Who this might be right for
Metastatic Melanoma
Memorial Sloan Kettering Cancer Center 70
Testing effectiveness (Phase 2)Ended earlyNCT03993379
What this trial is testing

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Who this might be right for
Solid TumorUnresectable or Metastatic Melanoma
CytomX Therapeutics 3
Early research (Phase 1)Study completedNCT03864042
What this trial is testing

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Melanoma
Pfizer 56
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT03391050
What this trial is testing

APR-246 in Combination With Dabrafenib in Resistant Patients With BRAF V600 Mutant Melanoma

Who this might be right for
Melanoma
Aprea Therapeutics 3
Early research (Phase 1)WithdrawnNCT02300935
What this trial is testing

Study of Trametinib and Nab-paclitaxel in Patients With Melanoma

Who this might be right for
Melanoma
SCRI Development Innovations, LLC
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406
What this trial is testing

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Who this might be right for
Advanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more
ECOG-ACRIN Cancer Research Group 150
Early research (Phase 1)Active Not RecruitingNCT04616248
What this trial is testing

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+10 more
University of Southern California 14
Early research (Phase 1)Study completedNCT01910181
What this trial is testing

Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanoma

Who this might be right for
Malignant Melanoma
Hoffmann-La Roche 46
Testing effectiveness (Phase 2)Looking for participantsNCT07237100
What this trial is testing

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Who this might be right for
Advanced Unresectable MelanomaMetastatic Melanoma
Kevin Kim, MD 10
Testing effectiveness (Phase 2)Study completedNCT04493203
What this trial is testing

Nivolumab Plus Axitinib in Patients With Anti-PD1 Refractory Advanced Melanoma

Who this might be right for
Advanced MelanomaUnresectable Melanoma
Yana Najjar 31
Testing effectiveness (Phase 2)Study completedNCT03484923
What this trial is testing

Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma
Novartis Pharmaceuticals 196
Early research (Phase 1)Study completedNCT00418496
What this trial is testing

Interleukin-2 With Sorafenib (BAY 43-9006) for Unresectable or Metastatic Clear Cell Renal Carcinoma (RCC) and Metastatic Melanoma

Who this might be right for
Renal CancerMelanoma
Ohio State University Comprehensive Cancer Center 17
Testing effectiveness (Phase 2)Study completedNCT04091217
What this trial is testing

Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma

Who this might be right for
Melanoma
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)Looking for participantsNCT05896839
What this trial is testing

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+10 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Study completedNCT00602576
What this trial is testing

Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma

Who this might be right for
Melanoma (Skin)
Abramson Cancer Center at Penn Medicine 169
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