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Results for “Unresectable Solid Tumor”

449 trials

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Showing 20 of 449 results

Early research (Phase 1)Looking for participantsNCT05176483
What this trial is testing

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)Urothelial Carcinoma (UC)+7 more
Exelixis 1,314
Early research (Phase 1)Not Yet RecruitingNCT06800196
What this trial is testing

KNT-0916 in Treatment of Unresectable or Metastatic Solid Tumors with FGFR2 Alterations

Who this might be right for
Solid Tumors with FGFR2 Alterations, Adult
KinoTeck Therapeutics Co., Ltd 151
Early research (Phase 1)Study completedNCT02070549
What this trial is testing

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the LiverMetastatic Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI) 46
Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Early research (Phase 1)Looking for participantsNCT07524322
What this trial is testing

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Who this might be right for
Breast CancerOvarian CancerEndometrial Cancer+6 more
Regor Pharmaceuticals Inc. 63
Early research (Phase 1)Ended earlyNCT02751528
What this trial is testing

QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer

Who this might be right for
Cancer
NantBioScience, Inc. 3
Early research (Phase 1)Study completedNCT00084877
What this trial is testing

Irinotecan and 3-AP in Treating Patients With Metastatic or Unresectable Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 36
Early research (Phase 1)Study completedNCT01822522
What this trial is testing

Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus

Who this might be right for
Advanced Malignant Solid NeoplasmHIV InfectionMetastatic Malignant Solid Neoplasm+2 more
National Cancer Institute (NCI) 36
Early research (Phase 1)UnknownNCT00004173
What this trial is testing

Oxaliplatin and Paclitaxel in Treating Patients With Metastatic or Unresectable Cancer

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT03993379
What this trial is testing

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Who this might be right for
Solid TumorUnresectable or Metastatic Melanoma
CytomX Therapeutics 3
Early research (Phase 1)Study completedNCT03864042
What this trial is testing

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Melanoma
Pfizer 56
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Early research (Phase 1)UnknownNCT04987112
What this trial is testing

Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors

Who this might be right for
Solid TumorCancer Metastatic
CanWell Pharma Inc. 36
Early research (Phase 1)Study completedNCT00121264
What this trial is testing

17-AAG and Sorafenib in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Study completedNCT00021047
What this trial is testing

Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor

Who this might be right for
Esophageal CancerExtrahepatic Bile Duct CancerGastric Cancer+3 more
National Institutes of Health Clinical Center (CC)
Early research (Phase 1)Looking for participantsNCT05803382
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Malignant Solid NeoplasmStage IV Colorectal Cancer AJCC v8+2 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Ended earlyNCT04003623
What this trial is testing

Efficacy and Safety of Pemigatinib in Participants With Solid Tumors With FGFR Mutations or Translocations (FIGHT-208)

Who this might be right for
Advanced or Metastatic Solid TumorsFGFR MutationsFGFR Translocations
Incyte Corporation 1
Testing effectiveness (Phase 2)Ended earlyNCT03822117
What this trial is testing

Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

Who this might be right for
Solid Tumor Malignancy
Incyte Corporation 111
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
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