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Results for “Unresectable Synovial Sarcoma”

18 trials

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Showing 18 of 18 results

Early research (Phase 1)Looking for participantsNCT05711615
What this trial is testing

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Who this might be right for
Metastatic Dedifferentiated LiposarcomaMetastatic LeiomyosarcomaMetastatic Myxofibrosarcoma+9 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06703346
What this trial is testing

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Who this might be right for
Neoplasms
Adaptimmune 87
Early research (Phase 1)Study completedNCT03009201
What this trial is testing

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Who this might be right for
Advanced Soft Tissue SarcomaLocally Advanced AngiosarcomaLocally Advanced Leiomyosarcoma+24 more
OHSU Knight Cancer Institute 16
Early research (Phase 1)Looking for participantsNCT06946225
What this trial is testing

ACTengine® IMA203 Combined With mRNA-4203

Who this might be right for
Cutaneous MelanomaSynovial Sarcoma
Immatics US, Inc. 15
Early research (Phase 1)Study completedNCT00720174
What this trial is testing

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Who this might be right for
Adult AngiosarcomaAdult Desmoplastic Small Round Cell TumorAdult Epithelioid Sarcoma+32 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)UnknownNCT04356872
What this trial is testing

The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma

Who this might be right for
Sarcoma, Soft Tissue
Fudan University 45
Early research (Phase 1)Ended earlyNCT06048705
What this trial is testing

Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Neoplasms
Adaptimmune 7
Testing effectiveness (Phase 2)Ended earlyNCT02601209
What this trial is testing

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

Who this might be right for
High Grade SarcomaMetastatic LeiomyosarcomaMetastatic Malignant Peripheral Nerve Sheath Tumor+16 more
National Cancer Institute (NCI) 151
Early research (Phase 1)Ended earlyNCT05943990
What this trial is testing

Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Who this might be right for
Neoplasms
Adaptimmune 5
Testing effectiveness (Phase 2)Study completedNCT00112463
What this trial is testing

Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma

Who this might be right for
Adult Alveolar Soft-part SarcomaAdult AngiosarcomaAdult Epithelioid Sarcoma+17 more
National Cancer Institute (NCI) 40
Large-scale testing (Phase 3)Ended earlyNCT01132547
What this trial is testing

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Who this might be right for
Cancer
University of South Florida 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT03967223
What this trial is testing

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Who this might be right for
Neoplasms
Adaptimmune 103
Testing effectiveness (Phase 2)UnknownNCT03989596
What this trial is testing

Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas

Who this might be right for
SarcomaAlveolar Soft Part SarcomaClear Cell Sarcoma+8 more
Maria Sklodowska-Curie National Research Institute of Oncology 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650986
What this trial is testing

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Who this might be right for
Advanced Fallopian Tube CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Melanoma+47 more
Roswell Park Cancer Institute 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05993299
What this trial is testing

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Who this might be right for
Neoplasms
Adaptimmune 7
Early research (Phase 1)Ended earlyNCT01469975
What this trial is testing

First in Man Study Investigating the Biodistribution, the Safety and Optimal Recommended Dose of a New Radiolabelled Monoclonal Antibody Targeting Frizzled Homolog 10

Who this might be right for
Sarcoma, Synovial
Centre Leon Berard 20
Testing effectiveness (Phase 2)Study completedNCT03063632
What this trial is testing

Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

Who this might be right for
Metastatic Myxoid LiposarcomaMetastatic Round Cell LiposarcomaMetastatic Synovial Sarcoma+13 more
National Cancer Institute (NCI) 28
Large-scale testing (Phase 3)Ended earlyNCT03520959
What this trial is testing

A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)

Who this might be right for
Synovial SarcomaCancerSoft Tissue Sarcoma+2 more
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 1