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Results for “Unresectable Uveal Melanoma”

27 trials

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Showing 20 of 27 results

Testing effectiveness (Phase 2)WithdrawnNCT03326258
What this trial is testing

Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmEstrogen Receptor NegativeGPNMB Positive+15 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT00072345
What this trial is testing

Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Intraocular MelanomaMelanoma (Skin)
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT05677373
What this trial is testing

Testing the Safety and Effectiveness of Combining Two Drugs, PLX2853 and Trametinib in the Treatment of Advanced Uveal Melanoma

Who this might be right for
Advanced Uveal MelanomaMetastatic Uveal MelanomaUnresectable Uveal Melanoma
Alliance for Clinical Trials in Oncology
Early research (Phase 1)Ended earlyNCT03865212
What this trial is testing

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Choroid Melanoma+10 more
Mayo Clinic 12
Testing effectiveness (Phase 2)Study completedNCT00738361
What this trial is testing

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed By Surgery

Who this might be right for
Intraocular Melanoma
Ohio State University Comprehensive Cancer Center 4
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)WithdrawnNCT05482074
What this trial is testing

Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2

Who this might be right for
Recurrent Metastatic MelanomaCutaneous MelanomaMucosal Melanoma+1 more
Dana-Farber Cancer Institute
Testing effectiveness (Phase 2)Looking for participantsNCT06413680
What this trial is testing

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

Who this might be right for
MelanomaClear-Cell Renal-Cell Carcinoma (ccRCC)Advanced Solid Tumors
Regeneron Pharmaceuticals 240
Testing effectiveness (Phase 2)Looking for participantsNCT06414590
What this trial is testing

Neoadjuvant Tebentafusp for Uveal Melanoma

Who this might be right for
Locally Advanced Unresectable Uveal Melanoma
Thomas Jefferson University 19
Testing effectiveness (Phase 2)Study completedNCT00121225
What this trial is testing

Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma

Who this might be right for
Ciliary Body and Choroid Melanoma, Medium/Large SizeExtraocular Extension MelanomaIris Melanoma+4 more
National Cancer Institute (NCI) 32
Early research (Phase 1)Study completedNCT00003022
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsIntraocular MelanomaLung Cancer+4 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT05628883
What this trial is testing

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

Who this might be right for
Metastatic MelanomaUnresectable MelanomaAcral Melanoma+7 more
H. Lee Moffitt Cancer Center and Research Institute 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT06784648
What this trial is testing

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma MetastaticMelanoma of SkinMelanoma BRAF V600E/K Mutated+7 more
BioInvent International AB 35
Testing effectiveness (Phase 2)Study completedNCT00096083
What this trial is testing

Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Cancer
Delcath Systems Inc. 56
Testing effectiveness (Phase 2)Study completedNCT02158520
What this trial is testing

Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Metastatic MelanomaMucosal MelanomaStage IV Cutaneous Melanoma AJCC v6 and v7+2 more
Academic and Community Cancer Research United 24
Testing effectiveness (Phase 2)Looking for participantsNCT06940739
What this trial is testing

Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

Who this might be right for
Unresectable MelanomaMetastatic MelanomaOcular Melanoma
Iovance Biotherapeutics, Inc. 42
Testing effectiveness (Phase 2)Study completedNCT01034787
What this trial is testing

Study of AntiCTLA4 in Patients With Unresectable or Metastatic Uveal Melanoma

Who this might be right for
Uveal Melanoma
AHS Cancer Control Alberta 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT03611868
What this trial is testing

APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Who this might be right for
Unresectable or Metastatic Melanoma or Advanced Solid TumorsMelanomaUveal Melanoma+5 more
Ascentage Pharma Group Inc. 230
Large-scale testing (Phase 3)Study completedNCT00324727
What this trial is testing

Hepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to Melanoma

Who this might be right for
Intraocular MelanomaMelanoma (Skin)Metastatic Cancer
Delcath Systems Inc. 93
Early research (Phase 1)Looking for participantsNCT07076550
What this trial is testing

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

Who this might be right for
Melanoma MetastaticUveal Melanoma, MetastaticMucosal Melanoma
Alpha-9 Oncology USA Inc. 50
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