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Results for “Unresectable or Metastatic Melanoma or Advanced Solid Tumors”

38 trials

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Showing 20 of 38 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04639219
What this trial is testing

T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations

Who this might be right for
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
AstraZeneca 102
Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Looking for participantsNCT06108479
What this trial is testing

Study of DF6215 in Patients with Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultSolid Tumor Cancer
Dragonfly Therapeutics 255
Testing effectiveness (Phase 2)Active Not RecruitingNCT05620134
What this trial is testing

Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
CancerTumor, SolidAdvanced Solid Tumor+19 more
Salubris Biotherapeutics Inc 263
Testing effectiveness (Phase 2)Looking for participantsNCT06413680
What this trial is testing

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

Who this might be right for
MelanomaClear-Cell Renal-Cell Carcinoma (ccRCC)Advanced Solid Tumors
Regeneron Pharmaceuticals 240
Testing effectiveness (Phase 2)Looking for participantsNCT06209580
What this trial is testing

AMT-253 in Patients With Advanced Solid Tumours

Who this might be right for
Malignant MelanomaAdvanced Solid Tumors
Multitude Therapeutics Inc. 96
Early research (Phase 1)Active Not RecruitingNCT04913285
What this trial is testing

Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Who this might be right for
Solid Tumor, AdultNon-small Cell Lung CancerMelanoma
Pierre Fabre Medicament 400
Early research (Phase 1)Study completedNCT03761017
What this trial is testing

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Who this might be right for
Squamous Cell Non Small Cell Lung CancerProstate Cancer MetastaticCutaneous Melanoma+3 more
MacroGenics 162
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Early research (Phase 1)Active Not RecruitingNCT05973487
What this trial is testing

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more
TScan Therapeutics, Inc. 840
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Not applicableActive Not RecruitingNCT05812027
What this trial is testing

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon Small Cell Lung Cancer+4 more
TScan Therapeutics, Inc. 1,150
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Early research (Phase 1)Study completedNCT00161187
What this trial is testing

Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor

Who this might be right for
Cancer
University of Medicine and Dentistry of New Jersey 37
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Very early researchEnded earlyNCT00499733
What this trial is testing

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 19
Early research (Phase 1)Ended earlyNCT04625205
What this trial is testing

A Clinical Study of the Safety and Activity of the Investigational Cell Therapy NEO-PTC-01 in Patients With Advanced Melanoma

Who this might be right for
Unresectable MelanomaMetastatic Melanoma
BioNTech US Inc. 22
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Early research (Phase 1)Study completedNCT03864042
What this trial is testing

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Melanoma
Pfizer 56
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