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Results for “Unresectable or Metastatic Sarcoma”

125 trials

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Showing 20 of 125 results

Testing effectiveness (Phase 2)Looking for participantsNCT06849986
What this trial is testing

IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)

Who this might be right for
Soft Tissue SarcomasAngiosarcomaFibrosarcoma+4 more
Fudan University 45
Testing effectiveness (Phase 2)Study completedNCT01553539
What this trial is testing

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

Who this might be right for
Bone CancerChondrosarcomaClear Cell Sarcoma of the Kidney+9 more
Wake Forest University Health Sciences 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02243605
What this trial is testing

Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Who this might be right for
Metastatic Ewing SarcomaMetastatic OsteosarcomaRecurrent Ewing Sarcoma+7 more
National Cancer Institute (NCI) 90
Early research (Phase 1)Ended earlyNCT02628535
What this trial is testing

Safety Study of MGD009 in B7-H3-expressing Tumors

Who this might be right for
MesotheliomaBladder CancerMelanoma+10 more
MacroGenics 67
Testing effectiveness (Phase 2)Study completedNCT01804374
What this trial is testing

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma

Who this might be right for
Metastatic OsteosarcomaRelapsed Osteosarcoma
Italian Sarcoma Group 38
Early research (Phase 1)Looking for participantsNCT06946225
What this trial is testing

ACTengine® IMA203 Combined With mRNA-4203

Who this might be right for
Cutaneous MelanomaSynovial Sarcoma
Immatics US, Inc. 15
Testing effectiveness (Phase 2)Study completedNCT01222767
What this trial is testing

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

Who this might be right for
Ewing's SarcomaPrimitive Neuroectodermal Tumor (PNET)Askin's Tumor of the Chest Wall+1 more
PharmaMar 17
Early research (Phase 1)Study completedNCT03126591
What this trial is testing

Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Eli Lilly and Company 41
Large-scale testing (Phase 3)WithdrawnNCT03342300
What this trial is testing

Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma

Who this might be right for
Progression-free SurvivalOverall SurvivalToxicity
Peking University People's Hospital
Testing effectiveness (Phase 2)UnknownNCT04138381
What this trial is testing

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST)

Who this might be right for
Maximum Tolerated DoseGISTMetastatic Adult Soft Tissue Sarcoma+2 more
Grupo Espanol de Investigacion en Sarcomas 30
Early research (Phase 1)Ended earlyNCT04627142
What this trial is testing

Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Boehringer Ingelheim 15
Early research (Phase 1)Ended earlyNCT02408861
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmAnal CarcinomaHIV Infection+7 more
National Cancer Institute (NCI) 79
Early research (Phase 1)Study completedNCT03761095
What this trial is testing

Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)

Who this might be right for
Leiomyosarcoma
PTC Therapeutics 41
Early research (Phase 1)Study completedNCT02015416
What this trial is testing

Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer

Who this might be right for
MelanomaOvarian CancerSarcoma+2 more
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 13
Very early researchWithdrawnNCT04877587
What this trial is testing

Gemcitabine With Ascorbate Including Adolescents

Who this might be right for
Soft Tissue SarcomaBone SarcomaUnresectable Soft Tissue Sarcoma+3 more
David Dickens
Testing effectiveness (Phase 2)Active Not RecruitingNCT03967223
What this trial is testing

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Who this might be right for
Neoplasms
USWM CT, LLC 103
Not applicableLooking for participantsNCT05868629
What this trial is testing

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

Who this might be right for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT00107419
What this trial is testing

S0423 Pemetrexed Disodium in Treating Patients With Recurrent and Unresectable or Metastatic Chondrosarcoma

Who this might be right for
Sarcoma
SWOG Cancer Research Network 75
Testing effectiveness (Phase 2)Study completedNCT02235701
What this trial is testing

Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma

Who this might be right for
Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcoma
ImmunityBio, Inc. 70
Testing effectiveness (Phase 2)Study completedNCT03056001
What this trial is testing

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

Who this might be right for
Soft Tissue Sarcoma, AdultSoft Tissue Sarcoma, Child
Wake Forest University Health Sciences 30
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