Not applicableStudy completedNCT03906214What this trial is testingEvidence-based Assessment of Medication Sensitivity in Acute Hepatic PorphyriaWho this might be right forPorphyrias University of South Florida 60
Not applicableLooking for participantsNCT01561157What this trial is testingLongitudinal Study of the PorphyriasWho this might be right forAcute PorphyriasCutaneous Porphyrias The American Porphyrias Expert Collaborative 1,500
Not applicableStudy completedNCT02240784What this trial is testingEXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)Who this might be right forAcute Hepatic Porphyria Alnylam Pharmaceuticals 136
Not applicableActive Not RecruitingNCT02935400What this trial is testingAcute Porphyria Biomarkers for Disease ActivityWho this might be right forAcute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria The University of Texas Medical Branch, Galveston 50
Large-scale testing (Phase 3)Study completedNCT03338816What this trial is testingENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)Who this might be right forAcute Hepatic PorphyriaAcute Intermittent PorphyriaPorphyria, Acute Intermittent+4 more Alnylam Pharmaceuticals 94
Not applicableEnded earlyNCT03547297What this trial is testingINSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHPWho this might be right forAcute Hepatic PorphyriaHepatic PorphyriasAcute Intermittent Porphyria (AIP)+4 more Alnylam Pharmaceuticals 212
Testing effectiveness (Phase 2)Ended earlyNCT02922413What this trial is testingPanhematin for Prevention of Acute Attacks of PorphyriaWho this might be right forAcute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria The University of Texas Medical Branch, Galveston 13
Testing effectiveness (Phase 2)Study completedNCT05854784What this trial is testingStudy to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Variegate Porphyria (VP)Who this might be right forVariegate Porphyria Clinuvel Pharmaceuticals Limited 6
Not applicableApproved For MarketingNCT04056481What this trial is testingExpanded Access Protocol of Givosiran for Patients With Acute Hepatic PorphyriaWho this might be right forAcute Hepatic Porphyria Alnylam Pharmaceuticals
Not applicableStudy completedNCT01568554What this trial is testingClinical Diagnosis of Acute PorphyriaWho this might be right forHereditary Coproporphyria (HCP)Acute Intermittent Porphyria (AIP)Variegate Porphyria (VP) University of California, San Francisco 148