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Results for “Venetoclax”

709 trials

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Showing 20 of 709 results

Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Testing effectiveness (Phase 2)Looking for participantsNCT07514936
What this trial is testing

Venetoclax-Azacitidine in Combination With Chidamide and CAG in Fit Older Patients With Acute Myeloid Leukaemia

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia (AML)Elderly Patients
Chinese PLA General Hospital 120
Testing effectiveness (Phase 2)Ended earlyNCT06563804
What this trial is testing

Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML

Who this might be right for
Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)/AMLChronic Myelomonocytic Leukemia (CMML)
Servier Bio-Innovation LLC 13
Early research (Phase 1)Active Not RecruitingNCT04447716
What this trial is testing

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Follicular LymphomaRecurrent Indolent Adult Non-Hodgkin Lymphoma+5 more
Thomas Jefferson University 4
Not applicableNot Yet RecruitingNCT06841952
What this trial is testing

Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Naïve Participants With Acute Myeloid Leukemia

Who this might be right for
AML, Adult
The First Affiliated Hospital of Soochow University 158
Testing effectiveness (Phase 2)WithdrawnNCT05486481
What this trial is testing

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

Who this might be right for
AL AmyloidosisLight Chain (AL) AmyloidosisSystemic Light Chain Disease
Alfred Chung, MD
Testing effectiveness (Phase 2)Looking for participantsNCT04855695
What this trial is testing

Avo In R/R And Previously Untreated MCL

Who this might be right for
Mantle Cell LymphomaRefractory Lymphoma
Austin I Kim 72
Testing effectiveness (Phase 2)Study completedNCT04146038
What this trial is testing

Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyeloblasts 10 Percent or More of Bone Marrow Nucleated Cells+5 more
Rutgers, The State University of New Jersey 5
Not applicableStudy completedNCT04178317
What this trial is testing

The Safety and Efficacy of Venetoclax for Participants With Chronic Lymphocytic Leukemia (CLL) Used in Routine Clinical Practice

Who this might be right for
Cancer, Chronic Lymphocytic Leukemia (CLL)
AbbVie 14
Testing effectiveness (Phase 2)Ended earlyNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Study completedNCT02287233
What this trial is testing

A Study Evaluating Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naïve Participants With Acute Myelogenous Leukemia

Who this might be right for
Acute Myelogenous LeukemiaAML
AbbVie 94
Testing effectiveness (Phase 2)Looking for participantsNCT05099471
What this trial is testing

Efficacy of Venetoclax in Combination With Rituximab in Waldenström's Macroglobulinemia

Who this might be right for
Waldenstrom MacroglobulinemiaTreatment Naive
Christian Buske 80
Testing effectiveness (Phase 2)WithdrawnNCT06770257
What this trial is testing

Daunorubicin, Cytarabine Liposomes Plus Venetoclax vs Azacitidine Plus Venetoclax in AML Patients Unfit for Intensive Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Institute of Hematology & Blood Diseases Hospital, China
Testing effectiveness (Phase 2)Active Not RecruitingNCT02250937
What this trial is testing

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 116
Testing effectiveness (Phase 2)Looking for participantsNCT06611839
What this trial is testing

Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML

Who this might be right for
AMLIDH1 MutationTreatment
Institute of Hematology & Blood Diseases Hospital, China 29
Large-scale testing (Phase 3)Looking for participantsNCT07007312
What this trial is testing

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Who this might be right for
Acute Myeloid Leukemia (AML)
Kura Oncology, Inc. 1,300
Testing effectiveness (Phase 2)WithdrawnNCT03856112
What this trial is testing

Ixazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapsed or Refractory Multiple Myeloma

Who this might be right for
Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myelomat(11;14) Negative
National Cancer Institute (NCI)
Not applicableLooking for participantsNCT07254312
What this trial is testing

Correlation of Venetoclax Plasma Concentrations With Toxicity of Hypometilating Agents and Venetoclax Combination for Acute Myeloid Leukemia Patients in Remission.

Who this might be right for
AML (Acute Myelogenous Leukemia
Fondazione IRCCS Policlinico San Matteo di Pavia 14
Early research (Phase 1)Ended earlyNCT04274907
What this trial is testing

A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Who this might be right for
Non Small Cell Lung CancerCancer
AbbVie 2
Testing effectiveness (Phase 2)Looking for participantsNCT04169737
What this trial is testing

Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Who this might be right for
Recurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic LymphomaRefractory Chronic Lymphocytic Leukemia+1 more
M.D. Anderson Cancer Center 168
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