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Results for “WHO Grade 4 Glioma”

69 trials

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Showing 20 of 69 results

Testing effectiveness (Phase 2)Study completedNCT01854554
What this trial is testing

Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT)

Who this might be right for
Brain Cancer
M.D. Anderson Cancer Center 90
Early research (Phase 1)Ended earlyNCT00915694
What this trial is testing

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Who this might be right for
Brain and Central Nervous System Tumors
Abramson Cancer Center at Penn Medicine 15
Testing effectiveness (Phase 2)Study completedNCT02330562
What this trial is testing

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Who this might be right for
Malignant GliomaGlioblastoma
Celgene 121
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195139
What this trial is testing

Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM

Who this might be right for
Glioblastoma Multiforme
University of Sydney 103
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Early research (Phase 1)Study completedNCT02903069
What this trial is testing

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Who this might be right for
GlioblastomaMalignant Glioma
Celgene 66
Not applicableStudy completedNCT03471546
What this trial is testing

Early Palliative Care Intervention in Malignant Glioma

Who this might be right for
Malignant Glioma
Duke University 12
Large-scale testing (Phase 3)Looking for participantsNCT06160492
What this trial is testing

Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)

Who this might be right for
5-aminolevulinic AcidFluorescence-guided Resection
Lee's Pharmaceutical Limited 144
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Not applicableStudy completedNCT01493219
What this trial is testing

Biomarkers for Prognosis of Glioblastoma (GBM)

Who this might be right for
Glioblastoma
University of Nebraska 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Testing effectiveness (Phase 2)Ended earlyNCT03927222
What this trial is testing

Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma

Who this might be right for
Glioblastoma
Mustafa Khasraw, MBChB, MD, FRCP, FRACP 6
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Early research (Phase 1)Ended earlyNCT00272870
What this trial is testing

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Who this might be right for
Glioblastoma Multiforme (WHO Grade IV)Anaplastic Astrocytoma (WHO Grade III)
Children's Hospital Medical Center, Cincinnati 1
Testing effectiveness (Phase 2)Study completedNCT02590263
What this trial is testing

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

Who this might be right for
Malignant GliomaGlioblastoma Multiforme
AbbVie 53
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