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Results for “WNT Pathway”

28 trials

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Showing 20 of 28 results

Early research (Phase 1)Ended earlyNCT05156905
What this trial is testing

Study of Docetaxel Combined with Cirmtuzumab in Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
University of California, San Diego 6
Not applicableStudy completedNCT04450589
What this trial is testing

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss

Who this might be right for
Androgenetic AlopeciaAndrogenic AlopeciaTelogen Effluvium+3 more
Arbor Life Labs 46
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableUnknownNCT05122741
What this trial is testing

Modulation of Fibrosis-inducing Pathways in Acute Myocardial Infarction

Who this might be right for
Myocardial InfarctionMyocardial FibrosisMyocardial Remodeling, Ventricular
University of Messina 50
Large-scale testing (Phase 3)Ended earlyNCT04520607
What this trial is testing

A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Biosplice Therapeutics, Inc. 276
Early research (Phase 1)Looking for participantsNCT06600321
What this trial is testing

Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular Carcinoma
Alnylam Pharmaceuticals 158
Large-scale testing (Phase 3)Study completedNCT04385303
What this trial is testing

Patient-Reported Outcomes in Evaluating Lorecivivint (SM04690) for Moderate to Severe Knee Osteoarthritis (STRIDES-1)

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 496
Not applicableStudy completedNCT02807714
What this trial is testing

Role of Podocan and Wnt Pathway Regulatory Molecules in Coronary Artery Disease

Who this might be right for
Coronary Artery Disease
Jennifer Victory, RN, CCRC 571
Testing effectiveness (Phase 2)Ended earlyNCT03706521
What this trial is testing

MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 13
Large-scale testing (Phase 3)Ended earlyNCT04931667
What this trial is testing

3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis

Who this might be right for
Osteoarthritis of the Knee
Biosplice Therapeutics, Inc. 72
Not applicableStudy completedNCT02806310
What this trial is testing

Podocan and Wnt Pathway in the Development of Aortopathy in Bicuspid Valve Disease

Who this might be right for
Aortic Valve Disease
Bassett Healthcare 29
Not applicableStudy completedNCT03636698
What this trial is testing

Effect of Chorioamnionitis on Platelet Activation and Placental Vessel Among Preterm Infants by Wnt-Flt1 Signal Pathway

Who this might be right for
ChorioamnionitisPlacenta DiseasesThrombocytopenia+1 more
Guangdong Women and Children Hospital 64
Not applicableActive Not RecruitingNCT07245225
What this trial is testing

Acute Effects of High Impact Exercise on Bone Metabolism

Who this might be right for
Health Adults
Loughborough University 15
Not applicableNo Longer AvailableNCT04681248
What this trial is testing

Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors

Who this might be right for
Esophageal NeoplasmAdenocarcinoma of the Gastroesophageal JunctionGastroEsophageal Cancer+7 more
Leap Therapeutics, Inc.
Not applicableStudy completedNCT02624934
What this trial is testing

Podocan and Wnt Pathway in Left Ventricular Remodeling of Aortic Stenosis

Who this might be right for
Aortic Valve Stenosis
Bassett Healthcare 9
Early research (Phase 1)Ended earlyNCT02687009
What this trial is testing

Niclosamide in Patients With Resectable Colon Cancer

Who this might be right for
Colon Cancer
Michael Morse, MD 1
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 595
Large-scale testing (Phase 3)Study completedNCT03928184
What this trial is testing

Patient-Reported and Radiographic Outcomes in Evaluating Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 501
Testing effectiveness (Phase 2)Study completedNCT06332612
What this trial is testing

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial

Who this might be right for
Oral Submucous Fibrosis
Ziauddin University 30
Early research (Phase 1)Looking for participantsNCT07312903
What this trial is testing

DPTX3186 in Wnt Pathway Activated Solid Tumors

Who this might be right for
Solid Tumors
Dewpoint Therapeutics 40
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