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Results for “WNT Pathway”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Ended earlyNCT03706521
What this trial is testing

MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT02278133
What this trial is testing

Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations

Who this might be right for
Metastatic Colorectal Cancer
Array BioPharma 20
Testing effectiveness (Phase 2)Study completedNCT03395080
What this trial is testing

DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma

Who this might be right for
Endometrial CancerUterine CancerOvarian Cancer+1 more
Leap Therapeutics, Inc. 111
Large-scale testing (Phase 3)Ended earlyNCT04931667
What this trial is testing

3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis

Who this might be right for
Osteoarthritis of the Knee
Biosplice Therapeutics, Inc. 72
Not applicableStudy completedNCT02806310
What this trial is testing

Podocan and Wnt Pathway in the Development of Aortopathy in Bicuspid Valve Disease

Who this might be right for
Aortic Valve Disease
Bassett Healthcare 29
Not applicableStudy completedNCT02624934
What this trial is testing

Podocan and Wnt Pathway in Left Ventricular Remodeling of Aortic Stenosis

Who this might be right for
Aortic Valve Stenosis
Bassett Healthcare 9
Testing effectiveness (Phase 2)Study completedNCT06332612
What this trial is testing

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial

Who this might be right for
Oral Submucous Fibrosis
Ziauddin University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT01878617
What this trial is testing

A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Who this might be right for
Medulloblastoma
St. Jude Children's Research Hospital 660
Not applicableStudy completedNCT03636698
What this trial is testing

Effect of Chorioamnionitis on Platelet Activation and Placental Vessel Among Preterm Infants by Wnt-Flt1 Signal Pathway

Who this might be right for
ChorioamnionitisPlacenta DiseasesThrombocytopenia+1 more
Guangdong Women and Children Hospital 64
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Ended earlyNCT02687009
What this trial is testing

Niclosamide in Patients With Resectable Colon Cancer

Who this might be right for
Colon Cancer
Michael Morse, MD 1
Not applicableEnded earlyNCT02221245
What this trial is testing

Wnt, Notch and Hedgehog Activity in Chemo-Naive Tumors Collected During Staging of Esophageal Cancer Patients

Who this might be right for
Esophageal Cancer
University of Miami 24
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 619
Not applicableStudy completedNCT04450602
What this trial is testing

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Female Subjects With Hair Loss

Who this might be right for
Androgenetic AlopeciaAndrogenic AlopeciaTelogen Effluvium+3 more
Arbor Life Labs 46
Not applicableStudy completedNCT04450589
What this trial is testing

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss

Who this might be right for
Androgenetic AlopeciaAndrogenic AlopeciaTelogen Effluvium+3 more
Arbor Life Labs 46
Not applicableUnknownNCT05122741
What this trial is testing

Modulation of Fibrosis-inducing Pathways in Acute Myocardial Infarction

Who this might be right for
Myocardial InfarctionMyocardial FibrosisMyocardial Remodeling, Ventricular
University of Messina 50
Early research (Phase 1)Ended earlyNCT05156905
What this trial is testing

Study of Docetaxel Combined with Cirmtuzumab in Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
University of California, San Diego 6
Not applicableStudy completedNCT02807714
What this trial is testing

Role of Podocan and Wnt Pathway Regulatory Molecules in Coronary Artery Disease

Who this might be right for
Coronary Artery Disease
Jennifer Victory, RN, CCRC 571
Early research (Phase 1)Ended earlyNCT03246399
What this trial is testing

The Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease

Who this might be right for
Degenerative Disc Disease
Biosplice Therapeutics, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT03122860
What this trial is testing

A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 700
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