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Results for “Wild-type Transthyretin Amyloidosis”

42 trials

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Showing 20 of 42 results

Not applicableStudy completedNCT04276220
What this trial is testing

Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery

Who this might be right for
Transthyretin AmyloidosisTransthyretin Cardiac AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis
Steen Hvitfeldt Poulsen 109
Not applicableLooking for participantsNCT06291805
What this trial is testing

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more
Steen Hvitfeldt Poulsen 120
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Not applicableStudy completedNCT03966105
What this trial is testing

Prevalence of Wild Type ATTR

Who this might be right for
Wild-type Transthyretin Amyloidosis
Oncology Institute of Southern Switzerland 94
Large-scale testing (Phase 3)Looking for participantsNCT06128629
What this trial is testing

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics 1,200
Testing effectiveness (Phase 2)Ended earlyNCT03702829
What this trial is testing

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Who this might be right for
Amyloidosis
Brigham and Women's Hospital 31
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Not applicableLooking for participantsNCT05950867
What this trial is testing

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Who this might be right for
PolyneuropathyAmyloidosis
Universitair Ziekenhuis Brussel 150
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Not applicableEnrolling By InvitationNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableUnknownNCT05814380
What this trial is testing

The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.

Who this might be right for
Transthyretin Amyloidosis
Katarzyna Holcman 100
Not applicableUnknownNCT02260466
What this trial is testing

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.

Who this might be right for
Heart DiseaseAgingAmyloidosis+1 more
French Cardiology Society 186
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Testing effectiveness (Phase 2)WithdrawnNCT02627820
What this trial is testing

The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart

Who this might be right for
Amyloidosis
Brigham and Women's Hospital
Not applicableUnknownNCT06499064
What this trial is testing

EOSS-ATTR Study (eHealth Based Operative Support System in ATTR-CM)

Who this might be right for
Heart FailureAmyloid CardiomyopathyATTR Amyloidosis Wild Type+1 more
Hospital Universitari de Bellvitge 50
Not applicableStudy completedNCT06029452
What this trial is testing

A Retrospective Validation Study To Identify Chart-Based Clinical Diagnosis Of Wild-Type Transthyretin Amyloid Cardiomyopathy (Attrwt-CM) And Non-Amyloid Heart Failure Among Patients With Heart Failure (HF).

Who this might be right for
ATTR-CM
Pfizer 558
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