Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Wildtype”

605 trials

Showing 20 of 605 results

Testing effectiveness (Phase 2)Looking for participantsNCT05983107
What this trial is testing

Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer

Who this might be right for
HR+/HER2- Advanced Breast CancerTargeted Therapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102
Early research (Phase 1)Study completedNCT06186492
What this trial is testing

Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Wave Life Sciences USA, Inc. 47
Not applicableStudy completedNCT02322736
What this trial is testing

Prospective Observational Study of 1st and 2nd Line Vectibix® Use in RAS-wt mCRC Pts to Evaluate Pattern of Use and ORR

Who this might be right for
Metastatic Colorectal Cancer
Amgen 218
Not applicableStudy completedNCT04665791
What this trial is testing

A Human Controlled Infection Study with Neisseria Lactamica in Malian Adults

Who this might be right for
Meningitis, Meningococcal
Center for Vaccine Development - Mali 55
Testing effectiveness (Phase 2)WithdrawnNCT06090318
What this trial is testing

Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss

Who this might be right for
Advanced Solid TumorCDKN2ANSCLC+7 more
Rain Oncology Inc
Testing effectiveness (Phase 2)UnknownNCT02967497
What this trial is testing

Clinical Study of YQ1 Plus Cisplatin-based Chemotherapy in Advanced NSCLC EGFR Wild Type

Who this might be right for
Epithelial Growth Factor Receptor Negative Non-small Cell Lung Cancer
Taipei Veterans General Hospital, Taiwan 56
Not applicableStudy completedNCT01834014
What this trial is testing

Exploratory Study in Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases

Who this might be right for
Liver MetastasisColorectal Cancer
EPS Corporation 110
Early research (Phase 1)Temporarily pausedNCT06905275
What this trial is testing

A Clinical Trial to Evaluate the Safety and Immunogenicity of Glycan-trimmed HIV-1 Nanoparticle Vaccine (UVAX-1107), Followed by Homologous or Wild-type HIV-1 Nanoparticle Vaccine (UVAX-1197) Boost, Each Adjuvanted With 3M-052-AF + Alum in Adult Participants Without HIV

Who this might be right for
HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID) 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07758062
What this trial is testing

Levetiracetam Extended-Release Plus Stupp Protocol for Hypoxic IDH-Wildtype Glioblastoma

Who this might be right for
Glioblastoma
Tianjin Medical University General Hospital 140
Testing effectiveness (Phase 2)Active Not RecruitingNCT03781986
What this trial is testing

APG-115 in Salivary Gland Cancer Trial

Who this might be right for
Malignant Salivary Gland CancerSalivary Gland Cancer
University of Michigan Rogel Cancer Center 41
Early research (Phase 1)Active Not RecruitingNCT03011671
What this trial is testing

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma of Brain
University of Chicago 10
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Testing effectiveness (Phase 2)Study completedNCT05278728
What this trial is testing

Phase IIa Study of Nimotuzumab to Treat Colorectal Cancer

Who this might be right for
Colorectal Cancer
Biotech Pharmaceutical Co., Ltd. 31
Large-scale testing (Phase 3)Looking for participantsNCT06662786
What this trial is testing

Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Janssen Research & Development, LLC 1,000
Not applicableWithdrawnNCT01631539
What this trial is testing

Chemoembolisation With CPT11 Loaded DC Bead With Cetuximab and 5FU/LV in First Line in Patients With KRAS Wildtype mCRC

Who this might be right for
Liver MetastasesColorectal Cancer
Universitaire Ziekenhuizen KU Leuven
Not applicableUnknownNCT05051592
What this trial is testing

Role of Circulating Tumour DNA Testing in Assessing for Alterations of Primary Anti-EGFR Resistance in RAS/RAF Wild-type Metastatic Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
National University Hospital, Singapore 40
Testing effectiveness (Phase 2)UnknownNCT03062800
What this trial is testing

Study of Thalidomide in Treatment of Advanced Nsclc (Dream-003)

Who this might be right for
Advanced Nsclc
Qilu Hospital of Shandong University 232
Testing effectiveness (Phase 2)Looking for participantsNCT05777278
What this trial is testing

Savolitinib Plus Docetaxel as 2L in EGFR/ALK/ROS1/MET ex14m-wildtype NSCLC With MET Overexpression

Who this might be right for
Non-small Cell Lung Cancer
The First Affiliated Hospital of Guangzhou Medical University 29
Testing effectiveness (Phase 2)UnknownNCT01410214
What this trial is testing

Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR Mutations

Who this might be right for
Non-small Cell Lung Cancer Stage IIIA
Chinese Lung Cancer Surgical Group 80
Testing effectiveness (Phase 2)WithdrawnNCT02785068
What this trial is testing

Evaluation of MM-151 + Nal-IRI + 5-FU + Leucovorin in RAS/RAF Wild-type Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Merrimack Pharmaceuticals
Next Page

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation