Not applicableNot Yet RecruitingNCT07313085What this trial is testingMechanisms of Fecal Incontinence in Wolfram SyndromeWho this might be right forWolfram SyndromeFecal Incontinence Hôpital Necker-Enfants Malades 20
Not applicableLooking for participantsNCT03988764What this trial is testingMonogenic Diabetes Misdiagnosed as Type 1Who this might be right forDiabetes Mellitus, Type 1Monogenic DiabetesNeonatal Diabetes+4 more McGill University Health Centre/Research Institute of the McGill University Health Centre 5,000
Testing effectiveness (Phase 2)UnknownNCT04940572What this trial is testingEfficacy Study of Daily Administration of VPA in Patients Affected by Wolfram SyndromeWho this might be right forWolfram Syndrome Centre d'Etude des Cellules Souches 23
Not applicableWithdrawnNCT01302327What this trial is testingGLP Analogs for Diabetes in Wolfram Syndrome PatientsWho this might be right forDiabetes Mellitus Associated With Genetic SyndromeWolfram Syndrome Hadassah Medical Organization
Not applicableNot Yet RecruitingNCT07336966What this trial is testingDoes Recessive Optic Atrophy Due to WFS1 Exist?Who this might be right forWolfram Syndrome 1Optic Atrophies, Hereditary Hôpital Necker-Enfants Malades 45
Testing effectiveness (Phase 2)UnknownNCT05659368What this trial is testingTirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1Who this might be right forWolfram Syndrome Ospedale San Raffaele 10
Not applicableActive Not RecruitingNCT07485413What this trial is testingLooking for VUS to Confirm Dominant Wolfram-like Syndrome Instead of Recessive Wolfram SyndromeWho this might be right forOptical Coherence Tomography (OCT) of the RetinaMutation Hôpital Necker-Enfants Malades 45
Not applicableStudy completedNCT03951298What this trial is testingI-Tracking Neurodegeneration in Early Wolfram SyndromeWho this might be right forWolfram Syndrome Washington University School of Medicine 127
Testing effectiveness (Phase 2)Active Not RecruitingNCT03717909What this trial is testingEfficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram SyndromeWho this might be right forWolfram Syndrome University of Birmingham 63
Not applicableStudy completedNCT02455414What this trial is testingTracking Neurodegeneration in Early Wolfram SyndromeWho this might be right forType 1 DiabetesDiabetes InsipidusDiabetes Mellitus+1 more Washington University School of Medicine 101
Not applicableLooking for participantsNCT02841553What this trial is testingWolfram Syndrome and WFS1-related Disorders International Registry and Clinical StudyWho this might be right forWolfram SyndromeDiabetes MellitusOptic Nerve Atrophy+3 more Washington University School of Medicine 5,000
Testing effectiveness (Phase 2)Study completedNCT02829268What this trial is testingA Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram SyndromeWho this might be right forWolfram SyndromeDiabetes MellitusOptic Nerve Atrophy+1 more Washington University School of Medicine 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT05676034What this trial is testingAMX0035 in Adult Patients With Wolfram SyndromeWho this might be right forWolfram Syndrome Amylyx Pharmaceuticals Inc. 12
Large-scale testing (Phase 3)UnknownNCT02882477What this trial is testingTreatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based TherapyWho this might be right forDiabetes MellitusIron Metabolism DisordersGastroduodenal Ulcer+3 more Hadassah Medical Organization 20