Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Worsening Heart Failure”

63 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 63 results

Large-scale testing (Phase 3)Ended earlyNCT03521934
What this trial is testing

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Who this might be right for
Heart FailureType 2 Diabetes Mellitus
Lexicon Pharmaceuticals 1,222
Testing effectiveness (Phase 2)Looking for participantsNCT06815471
What this trial is testing

CRF2 Agonist for the Treatment of Worsening Heart Failure

Who this might be right for
Worsening Heart Failure
Corteria Pharmaceuticals 300
Very early researchUnknownNCT05566600
What this trial is testing

Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure

Who this might be right for
Ischemic Heart FailureChronic Heart Failure
HELP Therapeutics Co., Ltd. 32
Large-scale testing (Phase 3)Study completedNCT00270374
What this trial is testing

A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.

Who this might be right for
Symptomatic Decompensated Congestive Heart FailureCongestive Heart Failure in Acute Coronary Syndrome
Scios, Inc. 498
Large-scale testing (Phase 3)Study completedNCT03988634
What this trial is testing

Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)
Novartis Pharmaceuticals 467
Not applicableStudy completedNCT04261452
What this trial is testing

Heart Failure Worsens Muscle Strength in COPD

Who this might be right for
COPDCHFMuscle Weakness
Mayron Faria de Oliveira 50
Not applicableUnknownNCT05731466
What this trial is testing

Exercise Right Ventricular Coupling in HFpEF

Who this might be right for
Heart Failure With Preserved Ejection FractionPulmonary Hypertension
Universitaire Ziekenhuizen KU Leuven 30
Not applicableLooking for participantsNCT07284446
What this trial is testing

Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients

Who this might be right for
Congestive Heart Failure ChronicCognitive Impairment, MildDepressive Symptoms Mild to Moderate in Severity
Lithuanian University of Health Sciences 300
Early research (Phase 1)Study completedNCT04908436
What this trial is testing

Learn How BAY94-8862 Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body in Adult Participants With Reduced Kidney Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Who this might be right for
Worsening Chronic Heart FailureChronic Kidney Disease
Bayer 33
Post-approval studies (Phase 4)UnknownNCT04062760
What this trial is testing

Safety and Efficacy of Early, seQUential Oral dIuretic Nephron blockAde In Acute Heart Failure

Who this might be right for
Acute Heart Failure
University of Parma 206
Testing effectiveness (Phase 2)Study completedNCT01955694
What this trial is testing

Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Disease Alone

Who this might be right for
Heart Failure
Bayer 72
Not applicableStudy completedNCT02133859
What this trial is testing

Adaptive Servo-ventilation Monitoring Study

Who this might be right for
Chronic Heart Failure
ResMed 40
Testing effectiveness (Phase 2)Study completedNCT01951638
What this trial is testing

Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure and Preserved Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-PRESERVED)

Who this might be right for
Heart Failure
Bayer 477
Not applicableUnknownNCT01081925
What this trial is testing

Congestive Heart Failure: Causes of Sudden Worsening

Who this might be right for
Congestive Heart Failure
University Hospital Hradec Kralove 100
Post-approval studies (Phase 4)Looking for participantsNCT06979726
What this trial is testing

Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure

Who this might be right for
Heart FailureVolume Overload
University of Florida 100
Large-scale testing (Phase 3)Study completedNCT03458325
What this trial is testing

Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure

Who this might be right for
Heart Failure
scPharmaceuticals, Inc. 27
Large-scale testing (Phase 3)Study completedNCT00288730
What this trial is testing

Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest

Who this might be right for
Heart Failure, CongestiveHeart Decompensation
Scios, Inc. 127
Not applicableEnded earlyNCT01364636
What this trial is testing

Accuracy of Urinary NGAL in Predicting CardioRenal Syndrome in Acute Heart Failure at Emergency - CYNDERELA-HF Study

Who this might be right for
Cardiorenal Syndrome
Pro-Cardiaco Hospital 180
Large-scale testing (Phase 3)Study completedNCT02468232
What this trial is testing

Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction

Who this might be right for
Heart Failure With Reduced Ejection Fraction (HF-rEF)
Novartis Pharmaceuticals 225
Large-scale testing (Phase 3)Study completedNCT00270400
What this trial is testing

A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure

Who this might be right for
Heart Failure, Congestive
Scios, Inc. 255
Load More Results