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Results for “XLP”

33 trials

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Showing 20 of 33 results

Large-scale testing (Phase 3)Looking for participantsNCT06910358
What this trial is testing

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Protoporphyria (XLP)
Disc Medicine, Inc 150
Not applicableStudy completedNCT01688895
What this trial is testing

Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-Linked Protoporphyria+5 more
Icahn School of Medicine at Mount Sinai 150
Large-scale testing (Phase 3)Looking for participantsNCT05005975
What this trial is testing

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 301
Not applicableStudy completedNCT00068146
What this trial is testing

Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) to Evaluate Autoimmune Lymphoproliferative Syndrome (ALPS) and ALPS-associated Lymphoma

Who this might be right for
Lymphoproliferative DisordersLymphoma
National Institute of Allergy and Infectious Diseases (NIAID) 77
Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Not applicableLooking for participantsNCT04902807
What this trial is testing

Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

Who this might be right for
Autoimmune Lymphoproliferative SyndromeAutoimmune CytopeniaAutoimmune Diseases+17 more
Institut National de la Santé Et de la Recherche Médicale, France 500
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Large-scale testing (Phase 3)Study completedNCT04402489
What this trial is testing

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 184
Early research (Phase 1)Study completedNCT00065390
What this trial is testing

Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome

Who this might be right for
Autoimmune DiseaseLymphatic DiseaseLymphoproliferative Disorder
National Institute of Allergy and Infectious Diseases (NIAID) 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT04641442
What this trial is testing

Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

Who this might be right for
NLRC4-GOF, AIFEC (Autoinflammation With Infantile Enterocolitis), XIAP Deficiency, CDC42 Mutations
Novartis Pharmaceuticals 17
Post-approval studies (Phase 4)Study completedNCT00893425
What this trial is testing

Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria

Who this might be right for
ProteinuriaDiabetic NephropathyChronic Kidney Disease
Gulhane School of Medicine 78
Large-scale testing (Phase 3)Study completedNCT03512314
What this trial is testing

Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency As Open Label Extension

Who this might be right for
XIAP DeficiencyNLRC4-MAS
AB2 Bio Ltd. 11
Not applicableLooking for participantsNCT00001350
What this trial is testing

Study of Autoimmune Lymphoproliferative Syndrome (ALPS)

Who this might be right for
Benign Lymphoproliferative Disorder
National Institute of Allergy and Infectious Diseases (NIAID) 1,200
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Large-scale testing (Phase 3)Study completedNCT03113760
What this trial is testing

Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency

Who this might be right for
NLRC4-MASXIAP Deficiency
AB2 Bio Ltd. 15
Large-scale testing (Phase 3)Study completedNCT06309823
What this trial is testing

A Single-patient Clinical Trial of MAS825 in a Patient With XIAP Deficiency

Who this might be right for
X-linked Lymphoproliferative Syndrome Type 2 (XLP-2)
The Hospital for Sick Children 1
Not applicableStudy completedNCT02979249
What this trial is testing

Oral Iron for Erythropoietic Protoporphyrias

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-linked Protoporphyria+1 more
Icahn School of Medicine at Mount Sinai 16
Not applicableEnrolling By InvitationNCT02422875
What this trial is testing

Comparative Autoantibody and Immunologic Cell Marker Study

Who this might be right for
Autoimmune DiseasesLupus Erythematosus, SystemicCommunicable Diseases
Emory University 2,500
Large-scale testing (Phase 3)Enrolling By InvitationNCT05883748
What this trial is testing

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

Who this might be right for
Erythropoietic Protoporphyria
Disc Medicine, Inc 230
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
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