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Results for “XLP”

36 trials

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Showing 20 of 36 results

Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Not applicableLooking for participantsNCT01561157
What this trial is testing

Longitudinal Study of the Porphyrias

Who this might be right for
Acute PorphyriasCutaneous Porphyrias
The American Porphyrias Expert Collaborative 1,500
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Early research (Phase 1)Study completedNCT00013689
What this trial is testing

Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome

Who this might be right for
Autoimmune DiseaseLymphoproliferative Disorder
National Institute of Allergy and Infectious Diseases (NIAID) 8
Large-scale testing (Phase 3)Study completedNCT04402489
What this trial is testing

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 184
Large-scale testing (Phase 3)Study completedNCT03512314
What this trial is testing

Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency As Open Label Extension

Who this might be right for
XIAP DeficiencyNLRC4-MAS
AB2 Bio Ltd. 11
Not applicableWithdrawnNCT01672918
What this trial is testing

Fluorodeoxyglucose Imaging Studies to Detect Lymphoma

Who this might be right for
Autoimmune Lymphoproliferative SyndromeLymphoma
National Institute of Allergy and Infectious Diseases (NIAID)
Large-scale testing (Phase 3)Looking for participantsNCT05005975
What this trial is testing

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 301
Large-scale testing (Phase 3)Study completedNCT03113760
What this trial is testing

Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency

Who this might be right for
NLRC4-MASXIAP Deficiency
AB2 Bio Ltd. 15
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Testing effectiveness (Phase 2)Study completedNCT00605657
What this trial is testing

Valproic Acid (Depakote[Registered Trademark]) to Treat Autoimmune Lymphoproliferative Syndrome (ALPS)

Who this might be right for
ALPSHypersplenismLymphadenopathy
Koneti Rao 6
Not applicableStudy completedNCT00068146
What this trial is testing

Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) to Evaluate Autoimmune Lymphoproliferative Syndrome (ALPS) and ALPS-associated Lymphoma

Who this might be right for
Lymphoproliferative DisordersLymphoma
National Institute of Allergy and Infectious Diseases (NIAID) 77
Not applicableLooking for participantsNCT07567131
What this trial is testing

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Porphyria (XLP)
Portal Therapeutics, Inc. 50
Not applicableLooking for participantsNCT00001350
What this trial is testing

Study of Autoimmune Lymphoproliferative Syndrome (ALPS)

Who this might be right for
Benign Lymphoproliferative Disorder
National Institute of Allergy and Infectious Diseases (NIAID) 1,200
Testing effectiveness (Phase 2)Study completedNCT00368355
What this trial is testing

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Who this might be right for
Acute Lymphoblastic LeukemiaNon Hodgkins LymphomaMyelodysplastic Syndrome+6 more
Baylor College of Medicine 46
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Study completedNCT00392951
What this trial is testing

Sirolimus for Autoimmune Disease of Blood Cells

Who this might be right for
Autoimmune PancytopeniaAutoimmune Lymphoproliferative Syndrome (ALPS)Evans Syndrome+6 more
Children's Hospital of Philadelphia 30
Post-approval studies (Phase 4)Study completedNCT00893425
What this trial is testing

Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria

Who this might be right for
ProteinuriaDiabetic NephropathyChronic Kidney Disease
Gulhane School of Medicine 78
Not applicableTemporarily Not AvailableNCT07603401
What this trial is testing

Expanded Access Program of Bitopertin For Participants With EPP or XLP

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Protoporphyria (XLP)
Disc Medicine, Inc
Testing effectiveness (Phase 2)Active Not RecruitingNCT04641442
What this trial is testing

Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

Who this might be right for
NLRC4-GOF, AIFEC (Autoinflammation With Infantile Enterocolitis), XIAP Deficiency, CDC42 Mutations
Novartis Pharmaceuticals 17
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