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Results for “Zanzalintinib”

38 trials

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Showing 20 of 38 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07691476
What this trial is testing

Multicenter Single-Arm Clinical Trial of Zanzalintinib and Pembrolizumab in Subjects With Resectable Clear Cell Renal Cell Carcinoma

Who this might be right for
Patients With Locally Advanced or Metastatic But Resectable Clear Cell Renal Cell Carcinoma
Yonsei University 48
Testing effectiveness (Phase 2)Looking for participantsNCT07042919
What this trial is testing

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaCirrhosisStage III Hepatocellular Carcinoma AJCC v8+1 more
Devalingam Mahalingam 59
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07682675
What this trial is testing

Study to Evaluate the Efficacy of Zanzalintinib in the Treatment of Relapsed or Metastatic Adenoid Cystic Carcinomas of the Head and Neck

Who this might be right for
Adenoid Cystic Carcinoma of the Salivary GlandRecurrenceMetastatic Disease
UNICANCER 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07185945
What this trial is testing

Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior Therapy

Who this might be right for
Advanced Urothelial Carcinoma
Guru Sonpavde 44
Testing effectiveness (Phase 2)Looking for participantsNCT06794229
What this trial is testing

Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis

Who this might be right for
Locally Advanced Renal Cell Carcinoma
Qian Qin 69
Testing effectiveness (Phase 2)Looking for participantsNCT06863311
What this trial is testing

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

Who this might be right for
Advanced Renal Cell CarcinomaMetastatic Renal Cell CarcinomaClear Cell Renal Cell Carcinoma
Karie Runcie 70
Early research (Phase 1)Looking for participantsNCT06957431
What this trial is testing

Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma

Who this might be right for
Advanced LeiomyosarcomaAdipocytic SarcomaAdvanced Liposarcoma
Washington University School of Medicine 18
Large-scale testing (Phase 3)Looking for participantsNCT07489495
What this trial is testing

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 758
Testing effectiveness (Phase 2)Looking for participantsNCT06698250
What this trial is testing

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

Who this might be right for
Hepatocellular Carcinoma
Anwaar Saeed 40
Testing effectiveness (Phase 2)Looking for participantsNCT06937866
What this trial is testing

Maintenance Zanzalintinib With Etoposide After HDCT in GCT

Who this might be right for
Germ Cell Tumor
Indiana University 38
Early research (Phase 1)Looking for participantsNCT06962332
What this trial is testing

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

Who this might be right for
Hepatic ImpairmentModerate Hepatic Impairment
Exelixis 20
Large-scale testing (Phase 3)Looking for participantsNCT07750158
What this trial is testing

Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

Who this might be right for
Colorectal Cancer
Exelixis 600
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07470489
What this trial is testing

Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer

Who this might be right for
Anaplastic Thyroid Cancer
M.D. Anderson Cancer Center 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07484139
What this trial is testing

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

Who this might be right for
Oral Cavity Squamous Cell CarcinomaHead and Neck Cancer
UNC Lineberger Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Looking for participantsNCT07193550
What this trial is testing

Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)

Who this might be right for
Bone Sarcomas
M.D. Anderson Cancer Center 70
Early research (Phase 1)Temporarily pausedNCT06968988
What this trial is testing

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Who this might be right for
Metastatic Soft-tissue Sarcoma
Washington University School of Medicine 18
Early research (Phase 1)Not Yet RecruitingNCT07773454
What this trial is testing

Study of Zanzalintinib in Children and Adolescents With Relapsed or Refractory Solid Tumors

Who this might be right for
CancerPediatric Cancer
Exelixis 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07578025
What this trial is testing

Zanzalintinib and MO-03 for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

Who this might be right for
Metastatic Clear Cell Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v8
City of Hope Medical Center 34
Early research (Phase 1)Ended earlyNCT06191796
What this trial is testing

Study of Zanzalintinib (XL092) + AB521 and Zanzalintinib + AB521 + Nivolumab in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Other Advanced Solid Tumors (STELLAR-009)

Who this might be right for
Advanced Clear Cell Renal Cell Carcinoma or Other Advanced Solid Tumors
Exelixis 25
Testing effectiveness (Phase 2)Looking for participantsNCT06959511
What this trial is testing

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Who this might be right for
Neoadjuvant TreatmentThyroid Cancer
M.D. Anderson Cancer Center 45
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