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Results for “mTOR”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00792766
What this trial is testing

Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous SclerosisAngiolipoma
Children's Hospital Medical Center, Cincinnati 20
Testing effectiveness (Phase 2)Study completedNCT01510119
What this trial is testing

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

Who this might be right for
Metastatic Clear Cell Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine 40
Post-approval studies (Phase 4)UnknownNCT03767660
What this trial is testing

Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation

Who this might be right for
Blue Rubber Bleb Nevus SyndromeVenous Malformation
Peking Union Medical College Hospital 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT04736589
What this trial is testing

Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway

Who this might be right for
Breast Cancer
Peking Union Medical College 270
Early research (Phase 1)Study completedNCT00973076
What this trial is testing

Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055

Who this might be right for
CancerSolid TumorsAdvanced Solid Malignancies
AstraZeneca 19
Early research (Phase 1)Study completedNCT01351350
What this trial is testing

Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies

Who this might be right for
Advanced Solid MalignanciesHematologic Malignancies
Millennium Pharmaceuticals, Inc. 68
Large-scale testing (Phase 3)WithdrawnNCT04139915
What this trial is testing

Effect of RTB101 on Illness Associated With Respiratory Tract Infections in the Elderly

Who this might be right for
Clinically Symptomatic Respiratory Illness
Restorbio Inc.
Testing effectiveness (Phase 2)Ended earlyNCT02315625
What this trial is testing

Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

Who this might be right for
Neuroendocrine TumorsNeuroendocrine CarcinomaNeuroendocrine Neoplasms+2 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Study completedNCT01467986
What this trial is testing

Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma

Who this might be right for
Neuroblastoma Recurrent
University of Regensburg 130
Early research (Phase 1)Temporarily pausedNCT01762410
What this trial is testing

Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors

Who this might be right for
Advanced Refractory Solid Tumors
Piramal Enterprises Limited 60
Not applicableStudy completedNCT00636090
What this trial is testing

Molecular, Genetic, and Genomic Assessments From Patients Treated With RAD001

Who this might be right for
Metastatic Hormone Refractory Prostate Cancer
Duke University 35
Not applicableStudy completedNCT02881697
What this trial is testing

MTOR and Adipose Tissue Inflammation

Who this might be right for
Obesity
University Hospital, Basel, Switzerland 80
Not applicableNot Yet RecruitingNCT05746689
What this trial is testing

Study of Sirolimus in IgG4-related Disease

Who this might be right for
IgG4-related Disease
Peking University International Hospital 20
Testing effectiveness (Phase 2)Study completedNCT03190174
What this trial is testing

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Who this might be right for
Ewing SarcomaPEComaEpithelioid Sarcoma+11 more
Sarcoma Oncology Research Center, LLC 34
Early research (Phase 1)Study completedNCT00781846
What this trial is testing

Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 17
Early research (Phase 1)Ended earlyNCT05840510
What this trial is testing

Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

Who this might be right for
Solid Tumor, AdultNSCLCAdvanced Cancer+2 more
Mirati Therapeutics Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT07558733
What this trial is testing

Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer

Who this might be right for
HR+ HER2- Breast Cancer
Faeth Therapeutics 32
Large-scale testing (Phase 3)Study completedNCT00414648
What this trial is testing

Efficacy and Safety of Sirolimus in LAM

Who this might be right for
Lymphangioleiomyomatosis
University of Cincinnati 89
Early research (Phase 1)Study completedNCT01854606
What this trial is testing

Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma

Who this might be right for
CD79 Mutant or ABC-subtype Diffuse Large B-Cell Lymphoma
Novartis Pharmaceuticals 31
Post-approval studies (Phase 4)Not Yet RecruitingNCT07203664
What this trial is testing

Use of Tacrolimus and MTOR Inhibitors With Anticipatory Therapy vs. Tacrolimus and Mycophenolic Acid With Universal Prophylaxis in Renal Recipients at High Risk of Posttransplant Cytomegalovirus.

Who this might be right for
Evaluate the Effectiveness of CMV Prevention Strategies in Kidney Transplant Recipients
Hospital Universitario La Paz 30
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