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Results for “nAMD”

150 trials

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Showing 20 of 150 results

Not applicableStudy completedNCT06178770
What this trial is testing

Injection Intervals in Real-world Neovascular Age-related Macular Degeneration (nAMD) Patients Switching to Brolucizumab With at Least 12 Months of Follow-up

Who this might be right for
Neovascular Age-related Macular Degeneration
Novartis Pharmaceuticals 414
Not applicableEnded earlyNCT05266495
What this trial is testing

Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

Who this might be right for
Neovascular Age-related Macular Degeneration
Novartis Pharmaceuticals 3
Not applicableStudy completedNCT07074054
What this trial is testing

Aflibercept 8 mg for nAMD: Early Anatomical and Functional Changes

Who this might be right for
Presence of Retinal FluidChanges in Macular Pigment Optical Density
Federico II University 40
Large-scale testing (Phase 3)Study completedNCT04264819
What this trial is testing

Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration

Who this might be right for
Neovascular Age-Related Macular Degeneration
Novartis Pharmaceuticals 295
Not applicableLooking for participantsNCT07249216
What this trial is testing

Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting

Who this might be right for
Age Related Macular Degeneration
Singapore National Eye Centre 117
Testing effectiveness (Phase 2)Looking for participantsNCT05672121
What this trial is testing

Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Who this might be right for
Age-Related Macular Degeneration
Chengdu Origen Biotechnology Co., Ltd. 42
Large-scale testing (Phase 3)Ended earlyNCT04757636
What this trial is testing

OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)

Who this might be right for
Neovascular Age-related Macular Degeneration
Opthea Limited 998
Post-approval studies (Phase 4)Active Not RecruitingNCT06795048
What this trial is testing

Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

Who this might be right for
Neovascular Age-related Macular Degeneration (nAMD)
Hoffmann-La Roche 274
Large-scale testing (Phase 3)Looking for participantsNCT07007065
What this trial is testing

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Who this might be right for
Neovascular Age-related Macular Degeneration
AbbVie 561
Testing effectiveness (Phase 2)Study completedNCT02507388
What this trial is testing

Safety and Pharmacokinetics of RTH258 in Subjects With Age-Related Macular Degeneration

Who this might be right for
Neovascular Age-Related Macular Degeneration
Alcon Research 51
Early research (Phase 1)Study completedNCT05639530
What this trial is testing

A Dose Escalation Study of IBI333 in Subjects With Neovascular Age-related Macular Degeneration

Who this might be right for
Neovascular Age-related Macular Degeneration
Innovent Biologics (Suzhou) Co. Ltd. 17
Early research (Phase 1)Not Yet RecruitingNCT07406438
What this trial is testing

To Evaluate the Safety, Pharmacokinetics, and Efficacy of GB10 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Who this might be right for
Neovascular Age-Related Macular Degeneration (nAMD)
Shenzhen Kexing Pharmaceutical Co., Ltd. 48
Not applicableActive Not RecruitingNCT06075147
What this trial is testing

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Who this might be right for
Visual ImpairmentNeovascular Age-related Macular Degeneration (nAMD)Diabetic Macula Edema (DME)
Bayer 2,500
Large-scale testing (Phase 3)Study completedNCT02540954
What this trial is testing

Efficacy and Safety of Two Different Aflibercept Regimens in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Who this might be right for
Macular Degeneration
Bayer 336
Not applicableEnded earlyNCT04764656
What this trial is testing

Observational Study to Evaluate Fluid Resolution and Effectiveness of Brolucizumab for nAMD in Portugal

Who this might be right for
Neovascular Age-related Macular Degeneration (nAMD)
Novartis Pharmaceuticals 81
Very early researchActive Not RecruitingNCT05099094
What this trial is testing

VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases

Who this might be right for
Neovascular Age-related Macular DegenerationDiabetic Macular EdemaRetinal Vein Occlusion
Shanghai BDgene Co., Ltd. 3
Large-scale testing (Phase 3)Study completedNCT01948830
What this trial is testing

Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD

Who this might be right for
Age-related Macular DegenerationChoroidal Neovascularization
Novartis Pharmaceuticals 650
Large-scale testing (Phase 3)Study completedNCT03823300
What this trial is testing

Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE)

Who this might be right for
Wet Macular Degeneration
Hoffmann-La Roche 658
Post-approval studies (Phase 4)UnknownNCT02681783
What this trial is testing

PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept

Who this might be right for
Central Serous ChorioretinopathyAge Related Macular DegenerationIdiopathic Poplypoidal Choroidal Vasculopathy
Sunnybrook Health Sciences Centre 90
Not applicableNot Yet RecruitingNCT07088445
What this trial is testing

Therapeutic Prospects of Faricimab Injection for Patients Affected by Neovascular Age-Related Macular Degeneration

Who this might be right for
Neovascular Age-related Macular Degeneration(nAMD)
Hui Peng 35
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