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Results for “nHCM”

9 trials

Showing 9 of 9 results

Testing effectiveness (Phase 2)Looking for participantsNCT07023614
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc. 165
Not applicableLooking for participantsNCT07483125
What this trial is testing

Valsalva SBP Drop and LVOT Obstruction

Who this might be right for
HCMoHCMnHCM
Shanghai Zhongshan Hospital 800
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Large-scale testing (Phase 3)Enrolling By InvitationNCT04848506
What this trial is testing

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

Who this might be right for
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 900
Testing effectiveness (Phase 2)Study completedNCT04164732
What this trial is testing

Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Novartis Pharmaceuticals 46
Testing effectiveness (Phase 2)Study completedNCT03442764
What this trial is testing

Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 59
Large-scale testing (Phase 3)Active Not RecruitingNCT06081894
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

Who this might be right for
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 500
Testing effectiveness (Phase 2)Looking for participantsNCT05836259
What this trial is testing

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Who this might be right for
Hypertrophic Cardiomyopathy
Tenaya Therapeutics 30
Large-scale testing (Phase 3)Study completedNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580

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