Not applicableStudy completedNCT04212351What this trial is testingFrameshift Peptides of Children With NF1Who this might be right forNeurofibromatosis Type 1 Children's National Research Institute 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06620354What this trial is testingClinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate CapsuleWho this might be right forNeurofibromatosis 1 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 33
Large-scale testing (Phase 3)UnknownNCT00921037What this trial is testingFirst Clinical Study of Erbium - Yttrium Aluminium Garnet (YAG) Laser Vaporization of Cutaneous NeurofibromasWho this might be right forCutaneous Neurofibromas Medical University of Vienna 12
Not applicableLooking for participantsNCT07233408What this trial is testingTailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health LiteracyWho this might be right forNeurofibromatosis 1 Massachusetts General Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT02964884What this trial is testingInterventions for Reading Disabilities in NF1Who this might be right forNeurofibromatosis Type 1Learning DisabilityReading Disability+1 more Vanderbilt University 120
Not applicableStudy completedNCT01851135What this trial is testingNeuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1Who this might be right forNeurofibromatosis Type 1 Nantes University Hospital 286
Testing effectiveness (Phase 2)Active Not RecruitingNCT03190915What this trial is testingTrametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic LeukemiaWho this might be right forJuvenile Myelomonocytic LeukemiaNeurofibromatosis Type 1 National Cancer Institute (NCI) 10
Testing effectiveness (Phase 2)Study completedNCT04481035What this trial is testingAntioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1Who this might be right forNeurofibromatosis 1 Children's Hospital Medical Center, Cincinnati 5
Not applicableStudy completedNCT01410006What this trial is testingNeurofibromatosis Type 1 Patient RegistryWho this might be right forNeurofibromatosis Type 1 Washington University School of Medicine 2,391
Not applicableUnknownNCT01218152What this trial is testingMicroarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTsWho this might be right forNeurofibromatosis Type 1 KU Leuven 20
Testing effectiveness (Phase 2)WithdrawnNCT03109301What this trial is testingMitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)Who this might be right forNeoplasms, Nerve TissueNeurofibromatosis 1Heredodegenerative Disorders, Nervous System+1 more National Cancer Institute (NCI)
Not applicableLooking for participantsNCT05361811What this trial is testingAcceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled TrialWho this might be right forNeurofibromatosis 1Noonan SyndromeLegius Syndrome+2 more National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Study completedNCT03090971What this trial is testingUse of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1Who this might be right forNeurofibromatosis 1Cutaneous Neurofibroma Fundação Educacional Serra dos Órgãos 7
Not applicableLooking for participantsNCT04395495What this trial is testingRASopathy BiorepositoryWho this might be right forRAS MutationNeurofibromatosis 1Noonan Syndrome+11 more Children's Hospital Medical Center, Cincinnati 1,000
Large-scale testing (Phase 3)Study completedNCT02471339What this trial is testingAcceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic PainWho this might be right forNeurofibromatosis Type 1Plexiform Neurofibromas National Cancer Institute (NCI) 66
Not applicableStudy completedNCT00314119What this trial is testingNatural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1Who this might be right forNeurofibromatosis Type 1Neurofibroma National Cancer Institute (NCI) 17
Early research (Phase 1)Study completedNCT00865644What this trial is testingTopical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1Who this might be right forNeurofibromatosis Type 1Cutaneous Neurofibromas Massachusetts General Hospital 11
Not applicableUnknownNCT01650142What this trial is testingModifying Genes in Neurofibromatosis 1Who this might be right forNeurofibromatosis 1 Assistance Publique - Hôpitaux de Paris 450